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IPR026895 is a ER membrane protein complex subunit 1.
<p>ER membrane protein complex subunit 1 is a component of the ER membrane protein complex (EMC, composed of EMC1, EMC2, EMC3, EMC4, EMC5 and EMC6). In Saccharomyces cerevisiae, the EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER) [[cite:PUB00061987]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Cellular component | ER membrane protein complex | A transmembrane protein complex located in the ER that is involved in ER-mitochondrial membrane tethering, which is required to facilitate lipid transfer from the ER to the mitochondrial membrane. In S. cerevisiae, it has six members: EMC1, EMC2, AIM27, EMC4, KRE27, and EMC6. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: ER membrane protein complex subunit 1-like [Cicer arietinum] gi|502131970|ref|XP_004501175.1| | 9 | ||
| – | PREDICTED: ER membrane protein complex subunit 1-like [Cicer arietinum] gi|502131970|ref|XP_004501175.1| | 7 | ||
| – | ER membrane protein complex subunit 1; TAIR: AT5G11560.1 catalytics; Swiss-Prot: sp|Q5ZL00|EMC1_CHICK ER membrane protein complex subunit 1; TrEMBL-Plants: tr|A0A072V2Z0|A0A072V2Z0_MEDTR ER membrane protein complex subunit-like protein; Found in the gene: LotjaGi1g1v0401700 | 21 | ||
| – | ER membrane protein complex subunit 1; TAIR: AT5G11560.1 catalytics; Swiss-Prot: sp|F8GAQ8|BAMB_FRAST Outer membrane protein assembly factor BamB; TrEMBL-Plants: tr|I1JUT9|I1JUT9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0126300_LC | 14 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 25.00 |