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IPR028879

Source: InterPro

Description

IPR028879 is a NADPH-dependent diflavin oxidoreductase 1.

<p>NDOR1, also known as Tah18 in budding yeast, is a conserved NAPDH-dependent diflavin reductase from eukaryotes. It is a component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery and part of an electron transfer chain functioning in an early step of cytosolic Fe/S biogenesis. It transfers electrons from NADPH to the Fe/S cluster DRE2 in budding yeasts or CIAPIN1 in humans [[cite:PUB00069566], [cite:PUB00067100]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0003958
Molecular function NADPH-hemoprotein reductase activity Catalysis of the reaction: NADPH + H+ + n oxidized hemoprotein = NADP+ + n reduced hemoprotein.
Subterm of

Associated Lotus transcripts 4

Transcript Name Description Predicted domains Domain count
Lj1g3v3328750.2
–
Domains
29
LotjaGi1g1v0551300.1
– NADPH--cytochrome P450 reductase; TAIR: AT3G02280.1 Flavodoxin family protein; Swiss-Prot: sp|Q6NPS8|NDOR1_ARATH NADPH-dependent diflavin oxidoreductase 1; TrEMBL-Plants: tr|I1N5D0|I1N5D0_SOYBN NADPH-dependent diflavin oxidoreductase 1; Found in the gene: LotjaGi1g1v0551300
Domains
30
LotjaGi1g1v0551300.3
– NADPH--cytochrome P450 reductase; TAIR: AT3G02280.1 Flavodoxin family protein; Swiss-Prot: sp|Q6NPS8|NDOR1_ARATH NADPH-dependent diflavin oxidoreductase 1; TrEMBL-Plants: tr|I1N5D0|I1N5D0_SOYBN NADPH-dependent diflavin oxidoreductase 1; Found in the gene: LotjaGi1g1v0551300
Domains
30
LotjaGi1g1v0551300.4
– NADPH--cytochrome P450 reductase; TAIR: AT3G02280.1 Flavodoxin family protein; Swiss-Prot: sp|Q6NPS8|NDOR1_ARATH NADPH-dependent diflavin oxidoreductase 1; TrEMBL-Plants: tr|I1N5D0|I1N5D0_SOYBN NADPH-dependent diflavin oxidoreductase 1; Found in the gene: LotjaGi1g1v0551300
Domains
30

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd06207 CDD 1 25.00