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IPR031121 is a KH domain containing protein RIK/BLOM7.
<p>This entry represents a group of KH domain containing proteins from eukaryotes, including RIK (rough sheath 2-interacting KH domain) from plants and BLOM7 (also known as KH homology domain-containing protein 4, KHDC4) from animals. KHDC4 is an RNA-binding protein involved in pre-mRNA splicing. It interacts with the PRP19C/Prp19 complex/NTC/Nineteen complex which is part of the spliceosome. KHDC4 binds preferentially RNA with A/C rich sequences and poly-C stretches. KHDC4 contains two type I K homology (KH) RNA-binding domains [[cite:PUB00086865], [cite:PUB00086864]].</p> <p>RIK1 interacts with rough sheath2 (RS2), which is a myb domain protein required to repress knox genes during leaf development [[cite:PUB00074396]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | RNA binding | Interacting selectively and non-covalently with an RNA molecule or a portion thereof. | ||
| Cellular component | Nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: protein RIK-like [Glycine max] gi|356568732|ref|XP_003552564.1| | 7 | ||
| – | PREDICTED: protein RIK-like isoform X2 [Cicer arietinum] gi|502091336|ref|XP_004489518.1| | 6 | ||
| – | PREDICTED: protein RIK-like isoform X2 [Cicer arietinum] gi|502091336|ref|XP_004489518.1| | 4 | ||
| – | Protein RIK; TAIR: AT3G29390.1 RS2-interacting KH protein; Swiss-Prot: sp|Q9LIA4|RIK_ARATH Protein RIK; TrEMBL-Plants: tr|I1N4J7|I1N4J7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0512300 | 8 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 25.00 |