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IPR031736 is a RNA exonuclease 1 homolog-like domain.
<p>This domain of unknown function is found in RNA exonuclease 1 homolog (also known as elongin A binding-protein 1) [[cite:PUB00076013]] and similar proteins such as exonuclease GOR from mammals and pqe-1 from C.elegans. Pqe-1 is a putative RNA exonuclease which protects neurons from the toxic effects of expanded poly-Q disease proteins [[cite:PUB00151919]]. It is unclear if this is through participation in the pathogenic mechanism underlying poly-Q-induced neurodegeneration or if it is by acting as a genetic modifier of the age of onset or progression of neurodegeneration [[cite:PUB00151919]]. Pqe-1 regulates gene expression in neurons [[cite:PUB00151920]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Uncharacterized protein TCM_016489 [Theobroma cacao] gi|508777803|gb|EOY25059.1| | 21 | ||
| – | Uncharacterized protein TCM_016489 [Theobroma cacao] gi|508777803|gb|EOY25059.1| | 4 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 50.00 |