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IPR032199 is a RecQ-mediated genome instability protein 1, C-terminal OB-fold domain.
<p>The dissolvasome is a protein complex that consists of BLM, a RecQ helicase that is product of the gene mutated in Bloom syndrome, topoisomerase IIIalpha (Top3alpha) and the RMI (RecQ-mediated genome instability) subcomplex, comprised of RMI1 and RMI2. The dissolvasome acts on double Holliday junction intermediates in homologous recombination, creating non-crossover products in a process termed 'dissolution' [[cite:PUB00076237], [cite:PUB00076238]].</p> <p>This entry represents the C-terminal oligo-nucleotide binding domain of Recq-mediated genome instability protein RMI1. This domain interacts with RMI2-OB folds to make up the RMI core complex. The RMI core interface is crucial for dissolvasome assembly and may have additional cellular roles as a docking hub for other proteins [[cite:PUB00075424], [cite:PUB00076224]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Nucleotide binding | Interacting selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | OSIGBa0132D06.6 [Oryza sativa Indica Group] gi|116309358|emb|CAH66440.1| | 9 | ||
| – | OSIGBa0132D06.6 [Oryza sativa Indica Group] gi|116309358|emb|CAH66440.1| | 9 | ||
| – | RecQ-mediated genome instability protein 1; TAIR: AT5G63540.1 recQ-mediated instability protein (DUF1767); Swiss-Prot: sp|Q7XRV0|RMI1_ORYSJ RecQ-mediated genome instability protein 1; TrEMBL-Plants: tr|I1KP59|I1KP59_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0418900 | 12 | ||
| – | RecQ-mediated genome instability protein 1; TAIR: AT5G63540.1 recQ-mediated instability protein (DUF1767); Swiss-Prot: sp|Q7XRV0|RMI1_ORYSJ RecQ-mediated genome instability protein 1; TrEMBL-Plants: tr|I1KP59|I1KP59_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0418900 | 12 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 25.00 |