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IPR032446 is a S phase cyclin A-associated protein in the endoplasmic reticulum, N-terminal.
<p>This entry represents a short highly conserved region close to the N terminus of SCAPER. SCAPER is an ER-localised protein and a substrate for cyclin A/Cdk2. One theory suggests that SCAPER functions to create a local high concentration of cyclin A2 in the cytoplasm. Alternatively, SCAPER might be acting to sequester a portion of cellular cyclin A2 that could then be readily available for nuclear translocation, which may be needed for exit from G0 phase [[cite:PUB00076322], [cite:PUB00076323]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Uncharacterized protein isoform 3 [Theobroma cacao] gi|508774726|gb|EOY21982.1| | 9 | ||
| – | S phase cyclin A-associated protein in the endoplasmic reticulum; TAIR: AT4G25160.1 U-box domain-containing protein kinase family protein; Swiss-Prot: sp|Q9BY12|SCAPE_HUMAN S phase cyclin A-associated protein in the endoplasmic reticulum; TrEMBL-Plants: tr|K7MKF6|K7MKF6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0252900 | 8 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 50.00 |