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IPR033740

Description

IPR033740 is a Aminopeptidase P.

<p>This entry represents the catalytic domain of aminopeptidases P, which are members of peptidase subfamily M24B, including aminopeptidases P1 (MEROPS identifier M24.005) and P2 (M24.009), both of which are assigned to E.C. 3.4.11.9. The enzymes are also known as X-Pro aminopeptidases, proline aminopeptidases and aminoacylproline aminopeptidases. They catalyse release of any N-terminal amino acid, including proline, that is linked with proline, even from a dipeptide or tripeptide [[cite:PUB00081757], [cite:PUB00046901], [cite:PUB00003579]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Molecular function Metalloaminopeptidase activity Catalysis of the hydrolysis of N-terminal amino acid residues from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.

Associated Lotus transcripts 5

Transcript Name Description Predicted domains Domain count
PREDICTED: probable Xaa-Pro aminopeptidase P-like [Glycine max] gi|356573012|ref|XP_003554659.1| 18
PREDICTED: probable Xaa-Pro aminopeptidase P-like [Cicer arietinum] gi|502161070|ref|XP_004512011.1| 15
Xaa-pro aminopeptidase, putative; TAIR: AT3G05350.1 Metallopeptidase M24 family protein; Swiss-Prot: sp|D1ZKF3|AMPP1_SORMK Probable Xaa-Pro aminopeptidase P; TrEMBL-Plants: tr|A0A0R0F3E9|A0A0R0F3E9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0773100 18
Xaa-pro aminopeptidase, putative; TAIR: AT3G05350.1 Metallopeptidase M24 family protein; Swiss-Prot: sp|D5GAC6|AMPP1_TUBMM Probable Xaa-Pro aminopeptidase P; TrEMBL-Plants: tr|K7MZY3|K7MZY3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0773100 20
Xaa-pro aminopeptidase, putative; TAIR: AT4G36760.1 aminopeptidase P1; Swiss-Prot: sp|D1ZKF3|AMPP1_SORMK Probable Xaa-Pro aminopeptidase P; TrEMBL-Plants: tr|G7KC66|G7KC66_MEDTR Xaa-pro aminopeptidase P; Found in the gene: LotjaGi2g1v0393500 18

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd01085 CDD 1 20.00