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IPR033895 is a UDP-GlcNAc-dolichyl-phosphate GlcNAc phosphotransferase.
<p>UDP-GlcNAc:dolichol-P GlcNAc-1-P transferase (GPT) catalyzes the transfer of GlcNAc-1-P from UDP-GlcNAc to dolichol-P to form GlcNAc-P-P-dolichol [[cite:PUB00081590]]. The reaction is the first step in the assembly of dolichol-linked oligosaccharide intermediates and is essential for eukaryotic N-glycosylation [[cite:PUB00001987]]. GPT activity has been identified in all eukaryotic cells examined to date. A series of six conserved motifs designated A through F, ranging in length from 5 to 13 amino acid residues, has been identified in this family. They have been determined to be important for stable expression, substrate binding, or catalytic activities [[cite:PUB00081591]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity | Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + dolichyl phosphate = UMP + N-acetyl-D-glucosaminyl-diphosphodolichol. | ||
| Biological process | Protein N-linked glycosylation | A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the N4 atom of peptidyl-asparagine, the omega-N of arginine, or the N1' atom peptidyl-tryptophan. | ||
| Biological process | Dolichol-linked oligosaccharide biosynthetic process | The chemical reactions and pathways resulting in the formation of dolichol-linked oligosaccharide, usually by a stepwise addition of glycosyl chains to endoplasmic reticulum membrane-bound dolichol-P. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: LOW QUALITY PROTEIN: UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase-like [Cicer arietinum] gi|502179051|ref|XP_004516363.1| | 11 | ||
| – | PREDICTED: LOW QUALITY PROTEIN: UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase-like [Cicer arietinum] gi|502179051|ref|XP_004516363.1| | 14 | ||
| – | Phospho-N-acetylmuramoyl-pentapeptide-transferase; TAIR: AT2G41490.1 UDP-glcnac-adolichol phosphate glcnac-1-p-transferase; Swiss-Prot: sp|P0CD61|GPT_DICDI UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase; TrEMBL-Plants: tr|I3SCK4|I3SCK4_LOTJA Uncharacterized protein; Found in the gene: LotjaGi5g1v0135100 | 11 | ||
| – | Phospho-N-acetylmuramoyl-pentapeptide-transferase; TAIR: AT2G41490.1 UDP-glcnac-adolichol phosphate glcnac-1-p-transferase; Swiss-Prot: sp|P0CD61|GPT_DICDI UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase; TrEMBL-Plants: tr|I3SCK4|I3SCK4_LOTJA Uncharacterized protein; Found in the gene: LotjaGi5g1v0135100 | 11 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 25.00 |