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IPR034004

Source: InterPro

Description

IPR034004 is a Pol I subunit A12, C-terminal zinc ribbon.

<p>The C-terminal zinc ribbon domain of subunit A12 in RNA polymerase (Pol) I (RPA12) is involved in intrinsic transcript cleavage [[cite:PUB00082137], [cite:PUB00056396]]. Eukaryote genomes are transcribed by three nuclear RNA polymerases (Pol I, II and III) that share some subunits. RPA12 in Pol I, RPB9 in Pol II, RPC11 in Pol III and TFS in archaea are distantly related to each other and to the TFIIS elongation factor of Pol II [[cite:PUB00082137]]. RPA12 has two zinc-binding domains separated by a flexible linker [[cite:PUB00082138]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0006379
Biological process MRNA cleavage Any process in which a pre-mRNA or mRNA molecule is cleaved at specific sites or in a regulated manner.
Subterm of

Associated Lotus transcripts 2

Transcript Name Description Predicted domains Domain count
Lj1g3v3384720.1
– PREDICTED: DNA-directed RNA polymerase I subunit RPA12-like isoform X1 [Cicer arietinum] gi|502132988|ref|XP_004501608.1|
Domains
12
LotjaGi1g1v0567000.1
– DNA-directed RNA polymerase subunit; TAIR: AT3G25940.1 TFIIB zinc-binding protein; Swiss-Prot: sp|Q1RMP0|RPA12_BOVIN DNA-directed RNA polymerase I subunit RPA12; TrEMBL-Plants: tr|G7JQD3|G7JQD3_MEDTR DNA-directed RNA polymerase subunit; Found in the gene: LotjaGi1g1v0567000
Domains
13

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd10507 CDD 1 50.00