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IPR034333 is a Glutathione S-transferases, class Zeta , N-terminal.
<p>GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress. The GST fold contains an N-terminal thioredoxin-fold domain and a C-terminal α helical domain, with an active site located in a cleft between the two domains. GSH binds to the N-terminal domain while the hydrophobic substrate occupies a pocket in the C-terminal domain [[cite:PUB00083280], [cite:PUB00083281]].</p> <p>This entry represents the N-terminal domain of the the glutathione S-transferase (GST) class Zeta subfamily members.</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Glutathione S-transferase; TAIR: AT2G02380.1 glutathione S-transferase (class zeta) 2; Swiss-Prot: sp|P57108|GSTZ_EUPES Glutathione S-transferase zeta class; TrEMBL-Plants: tr|I3SS38|I3SS38_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0003500 | 24 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd03191 | CDD | 1 | 100.00 |