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IPR036625

Description

IPR036625 is a E3-binding domain superfamily.

<p>A small domain of the E2 subunit of 2-oxo-acid dehydrogenases that is responsible for the binding of the E3 subunit. Proteins containing this domain include the branched-chain alpha-keto acid dehydrogenase complex of bacteria, which catalyses the overall conversion of alpha-keto acids to acyl-CoA and carbon dioxide; and the E3 binding protein of eukaryotic pyruvate dehydrogenase [[cite:PUB00019486]].</p> <p>The structure of the E3-binding domain has three helices with a close bundle fold and right-handed twist going up-and-down [[cite:PUB00050093]]. This structure arrangement is also found at the C-terminal of Nucleoid-associated protein Lsr2 and Protein Ku, in which it is a DNA-binding domain [[cite:PUB00092826]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Molecular function Transferase activity, transferring acyl groups Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor).

Associated Lotus transcripts 9

Transcript Name Description Predicted domains Domain count
Acetyltransferase component of pyruvate dehydrogenase complex; TAIR: AT3G52200.1 Dihydrolipoamide acetyltransferase, long form protein; Swiss-Prot: sp|Q0WQF7|ODP21_ARATH Dihydrolipoyllysine-residue acetyltransferase component 1 of pyruvate dehydrogenase complex, mitochondrial; TrEMBL-Plants: tr|I3SH23|I3SH23_LOTJA Acetyltransferase component of pyruvate dehydrogenase complex; Found in the gene: LotjaGi2g1v0157500 26
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; TAIR: AT3G25860.1 2-oxoacid dehydrogenases acyltransferase family protein; Swiss-Prot: sp|Q9SQI8|ODP24_ARATH Dihydrolipoyllysine-residue acetyltransferase component 4 of pyruvate dehydrogenase complex, chloroplastic; TrEMBL-Plants: tr|I1J6K8|I1J6K8_SOYBN Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; Found in the gene: LotjaGi2g1v0278200 25
Acetyltransferase component of pyruvate dehydrogenase complex; TAIR: AT3G13930.1 Dihydrolipoamide acetyltransferase, long form protein; Swiss-Prot: sp|Q8RWN9|ODP22_ARATH Dihydrolipoyllysine-residue acetyltransferase component 2 of pyruvate dehydrogenase complex, mitochondrial; TrEMBL-Plants: tr|A0A0B2S5Z1|A0A0B2S5Z1_GLYSO Acetyltransferase component of pyruvate dehydrogenase complex; Found in the gene: LotjaGi3g1v0419400 25
Acetyltransferase component of pyruvate dehydrogenase complex; TAIR: AT3G13930.1 Dihydrolipoamide acetyltransferase, long form protein; Swiss-Prot: sp|Q8RWN9|ODP22_ARATH Dihydrolipoyllysine-residue acetyltransferase component 2 of pyruvate dehydrogenase complex, mitochondrial; TrEMBL-Plants: tr|A0A0B2S5Z1|A0A0B2S5Z1_GLYSO Acetyltransferase component of pyruvate dehydrogenase complex; Found in the gene: LotjaGi3g1v0419400 25
Acetyltransferase component of pyruvate dehydrogenase complex; TAIR: AT1G54220.1 Dihydrolipoamide acetyltransferase, long form protein; Swiss-Prot: sp|Q5M729|ODP23_ARATH Dihydrolipoyllysine-residue acetyltransferase component 3 of pyruvate dehydrogenase complex, mitochondrial; TrEMBL-Plants: tr|A0A151T9E3|A0A151T9E3_CAJCA Acetyltransferase component of pyruvate dehydrogenase complex; Found in the gene: LotjaGi3g1v0419400 25
Acetyltransferase component of pyruvate dehydrogenase complex; TAIR: AT1G54220.1 Dihydrolipoamide acetyltransferase, long form protein; Swiss-Prot: sp|Q5M729|ODP23_ARATH Dihydrolipoyllysine-residue acetyltransferase component 3 of pyruvate dehydrogenase complex, mitochondrial; TrEMBL-Plants: tr|A0A151T9E3|A0A151T9E3_CAJCA Acetyltransferase component of pyruvate dehydrogenase complex; Found in the gene: LotjaGi3g1v0419400 25
Acetyltransferase component of pyruvate dehydrogenase complex; TAIR: AT1G54220.1 Dihydrolipoamide acetyltransferase, long form protein; Swiss-Prot: sp|Q5M729|ODP23_ARATH Dihydrolipoyllysine-residue acetyltransferase component 3 of pyruvate dehydrogenase complex, mitochondrial; TrEMBL-Plants: tr|A0A151T9E3|A0A151T9E3_CAJCA Acetyltransferase component of pyruvate dehydrogenase complex; Found in the gene: LotjaGi3g1v0419400 25
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; TAIR: AT3G06850.1 2-oxoacid dehydrogenases acyltransferase family protein; Swiss-Prot: sp|Q9M7Z1|ODB2_ARATH Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial; TrEMBL-Plants: tr|A0A072V2G4|A0A072V2G4_MEDTR Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; Found in the gene: LotjaGi4g1v0338800 22
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; TAIR: AT1G34430.1 2-oxoacid dehydrogenases acyltransferase family protein; Swiss-Prot: sp|Q9C8P0|ODP25_ARATH Dihydrolipoyllysine-residue acetyltransferase component 5 of pyruvate dehydrogenase complex, chloroplastic; TrEMBL-Plants: tr|A0A0S3SNP9|A0A0S3SNP9_PHAAN Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; Found in the gene: LotjaGi5g1v0279000 23

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 11.11