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IPR037200

Source: InterPro

Description

IPR037200 is a Pre-mRNA-splicing factor Isy1 superfamily.

<p>This entry includes yeast Isy1 and it's homologues from plants and animals. In budding yeast, Isy1 is part of the NineTeen Complex (NTC), which is involved in spliceosome activation by specifying the interaction of U5 and U6 with pre-mRNA for their stable association with the spliceosome after U4 dissociation [[cite:PUB00084341]]. The S. pombe homologue is known as Cwf12.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0000350
Biological process Generation of catalytic spliceosome for second transesterification step Conformational rearrangement of the spliceosomal complex containing the RNA products from the 1st step of splicing to form the catalytic site for the second step of splicing.
Subterm of
Part of

Associated Lotus transcripts 1

Transcript Name Description Predicted domains Domain count
LotjaGi3g1v0043900.1
– Pre-mRNA-splicing factor ISY1; TAIR: AT3G18790.1 pre-mRNA-splicing factor ISY1-like protein; Swiss-Prot: sp|Q69ZQ2|ISY1_MOUSE Pre-mRNA-splicing factor ISY1 homolog; TrEMBL-Plants: tr|G7K4N4|G7K4N4_MEDTR Pre-mRNA-splicing factor ISY1; Found in the gene: LotjaGi3g1v0043900
Domains
8

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
SSF140102 SUPERFAMILY 1 100.00