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IPR037675 is a GPI ethanolamine phosphate transferase 3, N-terminal.
<p>GPI ethanolamine phosphate transferase 3 (also known as PIG-O) is an ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. It catalyzes the transfer of ethanolamine phosphate to the GPI third mannose which links the GPI-anchor to the C terminus of the proteins by an amide bond [[cite:PUB00087464]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
GO term | Namespace | Name | Definition | Relationships |
---|---|---|---|---|
Biological process | GPI anchor biosynthetic process | The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol group is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage. | ||
Molecular function | Mannose-ethanolamine phosphotransferase activity | Catalysis of the transfer of ethanolamine phosphate to a mannose residue in the GPI lipid precursor. |
Transcript | Name | Description | Predicted domains | Domain count |
---|---|---|---|---|
– | GPI ethanolamine phosphate transferase; TAIR: AT5G17250.1 Alkaline-phosphatase-like family protein; Swiss-Prot: sp|Q8TEQ8|PIGO_HUMAN GPI ethanolamine phosphate transferase 3; TrEMBL-Plants: tr|A0A0R0GV98|A0A0R0GV98_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0125700 | 14 | ||
– | GPI ethanolamine phosphate transferase; TAIR: AT5G17250.1 Alkaline-phosphatase-like family protein; Swiss-Prot: sp|Q8TEQ8|PIGO_HUMAN GPI ethanolamine phosphate transferase 3; TrEMBL-Plants: tr|A0A0R0GV98|A0A0R0GV98_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0317600 | 14 |
A list of co-occurring predicted domains within the L. japonicus gene space:
Predicted domain | Source | Observations | Saturation (%) |
---|---|---|---|
cd16023 | CDD | 1 | 50.00 |