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IPR038577

Source: InterPro

Description

IPR038577 is a GT10-like, C-terminal domain superfamily.

<p>Structural domains comprising this superfamily share the structure of the C-terminal domain of Glycosyltransferase family 10 (GT10). The C-terminal domain plays an important role in acceptor binding and specificity [[cite:PUB00097397]].</p> <p>Glycosyltransferase family 10 ([cazy:GT10]) comprises enzymes with two known activities; galactoside 3(4)-L-fucosyltransferase ([ec:2.4.1.65]) and galactoside 3-fucosyltransferase ([ec:2.4.1.152]).</p> <p>The galactoside 3-fucosyltransferases display similarities with the alpha-2 and alpha-6-fucosyltranferases [[cite:PUB00001989]]. The biosynthesis of the carbohydrate antigen sialyl Lewis X (sLe(x)) is dependent on the activity of an galactoside 3-fucosyltransferase. This enzyme catalyses the transfer of fucose from GDP-beta-fucose to the 3-OH of N-acetylglucosamine present in lactosamine acceptors [[cite:PUB00006364]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Associated Lotus transcripts 2

Transcript Name Description Predicted domains Domain count
LotjaGi4g1v0074500.1
– Alpha 1,3 fucosyltransferase; TAIR: AT1G49710.1 fucosyltransferase 12; Swiss-Prot: sp|Q9LJK1|FUT11_ARATH Glycoprotein 3-alpha-L-fucosyltransferase A; TrEMBL-Plants: tr|A0A0L9VAP5|A0A0L9VAP5_PHAAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0074500
Domains
12
LotjaGi5g1v0281100.1
– Alpha-(1,4)-fucosyltransferase; TAIR: AT1G71990.1 fucosyltransferase 13; Swiss-Prot: sp|Q9C8W3|FUT13_ARATH Alpha-(1,4)-fucosyltransferase; TrEMBL-Plants: tr|A0A072VP38|A0A072VP38_MEDTR Alpha-(1,4)-fucosyltransferase-like protein; Found in the gene: LotjaGi5g1v0281100
Domains
13

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
TRANSMEMBRANE Phobius 1 50.00