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IPR038922 is a Huntingtin-interacting protein K, UBA-like domain.
<p>HYPK, also called Huntingtin yeast partner K or Huntingtin yeast two-hybrid protein K, is an intrinsically unstructured Huntingtin (HTT)-interacting protein with chaperone-like activity. It is involved in regulating cell growth, cell cycle, unfolded protein response, and cell death [[cite:PUB00063297], [cite:PUB00088555], [cite:PUB00088556]]. Proteins matched by this entry contain an N-terminal ubiquitin-associated (UBA) region that shows high sequence similarity with that of eukaryotic nascent polypeptide-associated complex proteins (NAC), which is one of the cytosolic chaperones that contact the nascent polypeptide chains as they emerge from the ribosome and assist in post-translational processes [[cite:PUB00088554], [cite:PUB00088553]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Huntingtin-interacting K-like protein; TAIR: AT3G06610.1 DNA-binding enhancer protein-like protein; Swiss-Prot: sp|Q9NX55|HYPK_HUMAN Huntingtin-interacting protein K; TrEMBL-Plants: tr|A2Q2W3|A2Q2W3_MEDTR Huntingtin-interacting K-like protein; Found in the gene: LotjaGi6g1v0259100 | 5 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 100.00 |