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IPR039481 is a Exocyst complex component EXOC2/Sec5, N-terminal domain.
<p>This entry represent a domain found at the N terminus of Sec5 from budding yeasts and EXOC2/VPS51 from animals.</p> <p>In S. cerevisiae, Sec5 is an essential component of the exocyst complex, which is composed of Sec3, Sec5, Sec6, Sec8, Sec10, Sec15, Exo70 and Exo84 [[cite:PUB00069847]]. The exocyst complex tethers post-Golgi secretory vesicles to the plasma membrane before soluble NSF attachment protein receptor (SNARE)-mediated membrane fusion [[cite:PUB00069846]].</p> <p>In mammals, active form (GTP-bound) of Ral GTPase interacts with EXOC2 and Exo84 and regulates the assembly interface of a full octameric exocyst complex [[cite:PUB00068332]]. Similar to yeast exocyst, the mammalian exocyst has been directly linked to post-Golgi targeting of secretory vesicles to discreet membrane sites [[cite:PUB00068332]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Exocyst complex component, putative; TAIR: AT1G76850.1 exocyst complex component sec5; Swiss-Prot: sp|Q8S3U9|SEC5A_ARATH Exocyst complex component SEC5A; TrEMBL-Plants: tr|A0A1J7HXP8|A0A1J7HXP8_LUPAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0280500 | 9 | ||
| – | Exocyst complex component, putative; TAIR: AT1G76850.1 exocyst complex component sec5; Swiss-Prot: sp|Q8S3U9|SEC5A_ARATH Exocyst complex component SEC5A; TrEMBL-Plants: tr|A0A1J7HXP8|A0A1J7HXP8_LUPAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0280500 | 9 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 50.00 |