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IPR039557 is a AHAS, ACT domain.
<p>This entry represents the N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetolactate synthase (acetohydroxyacid synthase; AHAS). AHAS catalyses the first common step in the biosynthesis of the three branched-chain amino acids (leucine, isoleucine, and valine). The first step involves the condensation of either pyruvate or 2-ketobutyrate with the two-carbon hydroxyethyl fragment derived from another pyruvate molecule, covalently bound to the coenzyme thiamine diphosphate. Bacterial AHASs generally consist of regulatory and catalytic subunits. The effector (valine) binding sites are proposed to be located in two symmetrically related positions in the interface between a pair of N-terminal ACT domains with the C-terminal domain of IlvH contacting the catalytic dimer. Plants Arabidopsis and Oryza have tandem IlvH subunits; both the first and second ACT domain sequences are present in this entry [[cite:PUB00040493]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Acetolactate synthase, small subunit; TAIR: AT2G31810.1 ACT domain-containing small subunit of acetolactate synthase protein; Swiss-Prot: sp|Q93YZ7|ILVH2_ARATH Acetolactate synthase small subunit 2, chloroplastic; TrEMBL-Plants: tr|I3SMD8|I3SMD8_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0387300 | 16 | ||
| – | Acetolactate synthase small subunit; TAIR: AT2G31810.1 ACT domain-containing small subunit of acetolactate synthase protein; Swiss-Prot: sp|Q93YZ7|ILVH2_ARATH Acetolactate synthase small subunit 2, chloroplastic; TrEMBL-Plants: tr|I3SMD8|I3SMD8_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0387300 | 16 | ||
| – | Acetolactate synthase, small subunit; TAIR: AT2G31810.1 ACT domain-containing small subunit of acetolactate synthase protein; Swiss-Prot: sp|Q93YZ7|ILVH2_ARATH Acetolactate synthase small subunit 2, chloroplastic; TrEMBL-Plants: tr|I3SMD8|I3SMD8_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0387300 | 16 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd04878 | CDD | 1 | 33.33 |