Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message
IPR039683 is a Protein Lsm12-like.
<p>This entry represents Lsm12 and its homologues. Lsm12 is a putative RNA-binding and regulation protein that might be involved in mRNA degradation or tRNA splicing [[cite:PUB00044226]]. Recently, it was demonstrated that it binds nicotinic acid adenine dinucleotide phosphate (NAADP) that confers NAADP sensitivity to the two pore channel complex (TPCs) by acting as TPC accessory protein necessary for NAADP-evoked Ca2 release [[cite:PUB00101073]]. Therefore, further studies of the potential crosstalk between NAADP signaling and RNA regulation are required.</p> <p>Sm and Sm-like proteins of the Lsm (like Sm) domain family are generally involved in essential RNA-processing tasks [[cite:PUB00016606]]. All the LSM proteins are evolutionarily conserved in eukaryotes with an N-terminal Lsm domain to bind nucleic acids followed by a C-terminal region, some of which have a C-terminal methyltransferase domain.</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Protein LSM12 like; TAIR: AT1G24050.1 RNA-processing, Lsm domain-containing protein; Swiss-Prot: sp|Q6GP89|LSM12_XENLA Protein LSM12 homolog; TrEMBL-Plants: tr|I3SYU2|I3SYU2_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0162900 | 5 | ||
| – | Protein LSM12 like; TAIR: AT1G24050.1 RNA-processing, Lsm domain-containing protein; Swiss-Prot: sp|Q6GP89|LSM12_XENLA Protein LSM12 homolog; TrEMBL-Plants: tr|I3SYU2|I3SYU2_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0162900 | 5 | ||
| – | Protein LSM12 like; TAIR: AT1G24050.1 RNA-processing, Lsm domain-containing protein; Swiss-Prot: sp|Q6GP89|LSM12_XENLA Protein LSM12 homolog; TrEMBL-Plants: tr|I3SYU2|I3SYU2_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0162900 | 5 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| SM00995 | SMART | 1 | 33.33 |