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IPR039798

Source: InterPro

Description

IPR039798 is a Sulfhydryl oxidase.

<p>This entry contains sulfhydryl oxidases that are flavin-dependent [[cite:PUB00043720]]. Sulfhydryl oxidase 1 (QSOX1 or quiescin Q6) oxidizes sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide, permitting disulfide bond formation. QSOX1 is predominantly found in the Golgi [[cite:PUB00090112]]. Sulfhydryl oxidase 2 (QSOX2) is predominantly located in the plasma and in the nuclear membrane and regulates the sensitization of neuroblastoma cells for interferon-gamma-induced apoptosis [[cite:PUB00090113]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0016971
Molecular function Flavin-linked sulfhydryl oxidase activity Catalysis of the formation of disulfide bridges.
Subterm of

Associated Lotus transcripts 3

Transcript Name Description Predicted domains Domain count
LotjaGi3g1v0138800_LC.1
– Sulfhydryl oxidase; TAIR: AT1G15020.1 quiescin-sulfhydryl oxidase 1; Swiss-Prot: sp|Q6AUC6|QSOX1_ORYSJ Sulfhydryl oxidase 1; TrEMBL-Plants: tr|I1NFT7|I1NFT7_SOYBN Sulfhydryl oxidase; Found in the gene: LotjaGi3g1v0138800_LC
Domains
6
LotjaGi5g1v0331700.1
– Sulfhydryl oxidase; TAIR: AT2G01270.1 quiescin-sulfhydryl oxidase 2; Swiss-Prot: sp|Q9ZU40|QSOX2_ARATH Sulfhydryl oxidase 2; TrEMBL-Plants: tr|K7LLL4|K7LLL4_SOYBN Sulfhydryl oxidase; Found in the gene: LotjaGi5g1v0331700
Domains
27
LotjaGi5g1v0331700.2
– Sulfhydryl oxidase; TAIR: AT1G15020.2 quiescin-sulfhydryl oxidase 1; Swiss-Prot: sp|Q8W4J3|QSOX1_ARATH Sulfhydryl oxidase 1; TrEMBL-Plants: tr|A0A0B2PBV9|A0A0B2PBV9_GLYSO Sulfhydryl oxidase; Found in the gene: LotjaGi5g1v0331700
Domains
27

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
TRANSMEMBRANE Phobius 1 33.33