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IPR039799

Source: InterPro

Description

IPR039799 is a Sulfhydryl oxidase ALR/ERV.

<p>This entry contains FAD-dependent sulfhydryl oxidases, including ALR from animals and Erv from plants and fungi. ALR generates the disulfide bonds in CHCHD4/MIA40, which in turn is a chaperone required for disulfide bond formation and protein folding in the mitochondrial intermembrane space [[cite:PUB00090114]]. ERV1 from Arabidopsis is required for the import and folding of small cysteine-containing proteins in the mitochondrial intermembrane space [[cite:PUB00090115]]. Erv2 from<i>Saccharomyces cerevisiae</i>catalyzes disulfide bond formation in the endoplasmic reticulum lumen [[cite:PUB00090116]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0016971
Molecular function Flavin-linked sulfhydryl oxidase activity Catalysis of the formation of disulfide bridges.
Subterm of

Associated Lotus transcripts 1

Transcript Name Description Predicted domains Domain count
LotjaGi4g1v0245500.1
– Sulfhydryl oxidase; TAIR: AT1G49880.1 Erv1/Alr family protein; Swiss-Prot: sp|Q8GXX0|ERV1_ARATH FAD-linked sulfhydryl oxidase ERV1; TrEMBL-Plants: tr|A0A151SFK0|A0A151SFK0_CAJCA Sulfhydryl oxidase; Found in the gene: LotjaGi4g1v0245500
Domains
9

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
SSF69000 SUPERFAMILY 1 100.00