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IPR039812

Source: InterPro

Description

IPR039812 is a Vesicle-fusing ATPase.

<p>This family of vesicle-fusing ATPases includes NSF, an essential protein in membrane fusion events. NSF plays the role of a chaperone by activating SNAP receptor proteins (SNAREs) so that they can participate in membrane fusion. For subsequent rounds of fusion, the SNARE complex must be disassembled, and NSF, in conjunction with SNAPs, utilises its intrinsic ATPase activity to provide a driving force that disassembles SNARE complexes [[cite:PUB00090154], [cite:PUB00090155], [cite:PUB00080105]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0016887
Molecular function ATPase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
Subterm of
GO:0035494
Biological process SNARE complex disassembly The disaggregation of the SNARE protein complex into its constituent components. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.
Subterm of
Part of

Associated Lotus transcripts 1

Transcript Name Description Predicted domains Domain count
LotjaGi4g1v0055600.1
– ATP-dependent zinc metalloprotease FtsH; TAIR: AT4G04910.1 AAA-type ATPase family protein; Swiss-Prot: sp|Q9M0Y8|NSF_ARATH Vesicle-fusing ATPase; TrEMBL-Plants: tr|A0A0L9TKH7|A0A0L9TKH7_PHAAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0055600
Domains
18

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd00009 CDD 1 100.00