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IPR039865 is a Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma.
<p>Protein phosphatase 2A (PP2A) forms several holoenzyme complexes. The core enzyme consists of a catalytic C subunit (PP2Ac) and a regulatory A subunit (PR65) that is associated with a regulatory B subunit. The regulatory B subunit can be classified as a member of the B, B' or B'' families [[cite:PUB00007513]].</p> <p>PPP2R3C is a B'' family member and a regulatory B subunit of PP2A. It is also a subunit of the PP5/PPP2R3C complex. Both PP2A and PP5 are serine/threonine specific phosphatases. The PP5/PPP2R3C complex dephosphorylates P-glycoprotein/ABCB1 and down-regulates its expression and function [[cite:PUB00090241]]. This entry also includes TONNEAU2/FASS from Arabidopsis. TONNEAU2 is the B'' subunit of protein phosphatase 2A that regulates interphase microtubule nucleation [[cite:PUB00090242]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Biological process | Regulation of dephosphorylation | Any process that modulates the frequency, rate or extent of removal of phosphate groups from a molecule. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Serine/threonine-protein phosphatase 2A regulatory subunit B; TAIR: AT5G18580.1 tonneau 2 (TON2); Swiss-Prot: sp|Q9FEE2|TON2_ARATH Probable serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit TON2; TrEMBL-Plants: tr|A0A1J7I2N6|A0A1J7I2N6_LUPAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0345000 | 11 | ||
| – | Serine/threonine-protein phosphatase 2A regulatory subunit B; TAIR: AT5G18580.1 tonneau 2 (TON2); Swiss-Prot: sp|Q9FEE2|TON2_ARATH Probable serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit TON2; TrEMBL-Plants: tr|A0A1J7I2N6|A0A1J7I2N6_LUPAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0345000 | 12 | ||
| – | Serine/threonine-protein phosphatase 2A regulatory subunit B; TAIR: AT5G18580.1 tonneau 2 (TON2); Swiss-Prot: sp|Q9FEE2|TON2_ARATH Probable serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit TON2; TrEMBL-Plants: tr|A0A0L9TT07|A0A0L9TT07_PHAAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0424800 | 16 | ||
| – | Serine/threonine-protein phosphatase 2A regulatory subunit B; TAIR: AT5G18580.1 tonneau 2 (TON2); Swiss-Prot: sp|Q9FEE2|TON2_ARATH Probable serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit TON2; TrEMBL-Plants: tr|A0A1J7I2N6|A0A1J7I2N6_LUPAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0424800 | 11 | ||
| – | Serine/threonine-protein phosphatase 2A regulatory subunit B; TAIR: AT5G18580.1 tonneau 2 (TON2); Swiss-Prot: sp|Q9FEE2|TON2_ARATH Probable serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit TON2; TrEMBL-Plants: tr|B9RT18|B9RT18_RICCO Tonneau, putative; Found in the gene: LotjaGi4g1v0424800 | 11 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| SSF47473 | SUPERFAMILY | 1 | 20.00 |