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IPR039948

Source: InterPro

Description

IPR039948 is a Elongin-C.

<p>Elongin-C is a highly conserved protein found in a variety of multiprotein complexes in human, rat, fly, worm, and yeast cells [[cite:PUB00090343]]. Budding yeast elongin-C homologue, Elc1, forms a complex with Cul3 that is required for Pol II polyubiquitylation and degradation [[cite:PUB00072441]]. Elc1 also plays a role in global genomic repair [[cite:PUB00090344]]. In humans, elongin-C works as an adapter protein in the proteasomal degradation of target proteins via different E3 ubiquitin ligase complexes, including the von Hippel-Lindau ubiquitination complex CBC(VHL) [[cite:PUB00005233]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Associated Lotus transcripts 3

Transcript Name Description Predicted domains Domain count
LotjaGi3g1v0491300.1
– Transcription elongation factor B polypeptide 1; TAIR: AT5G59140.1 BTB/POZ domain-containing protein; Swiss-Prot: sp|Q2KII4|ELOC_BOVIN Elongin-C; TrEMBL-Plants: tr|A0A0S3SG76|A0A0S3SG76_PHAAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0491300
Domains
11
LotjaGi3g1v0491300.2
– Transcription elongation factor B polypeptide 1; TAIR: AT5G59140.1 BTB/POZ domain-containing protein; Swiss-Prot: sp|Q2KII4|ELOC_BOVIN Elongin-C; TrEMBL-Plants: tr|A0A0S3SG76|A0A0S3SG76_PHAAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0491300
Domains
11
LotjaGi3g1v0491300.3
– Transcription elongation factor B polypeptide 1; TAIR: AT5G59140.1 BTB/POZ domain-containing protein; Swiss-Prot: sp|Q2KII4|ELOC_BOVIN Elongin-C; TrEMBL-Plants: tr|A0A0S3SG76|A0A0S3SG76_PHAAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0491300
Domains
11

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd18321 CDD 1 33.33