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IPR001232 is a S-phase kinase-associated protein 1-like.
<p>This entry includes SKP1 and SKP1-like protein, elongin-C (also known as TCEB1). SKP1 is part of the E3 ubiquitin ligase complexes. Elongin-C has dual functions, works as a component of RNA polymerase II (Pol II) transcription elongation factor and as the substrate recognition subunit of a Cullin-RING E3 ubiquitin ligase [[cite:PUB00076434]].</p> <p>Mammlian S-phase kinase-associated protein 1 (SKP1) is an essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription [[cite:PUB00058708]]. It is also part of the ubiquitin E3 ligase complex (Skp1-Pam-Fbxo45) that controls the core epithelial-to-mesenchymal transition-inducing transcription factors [[cite:PUB00076424]]. Budding yeast Skp1 is a kinetochore protein found in several complexes, including the SCF ubiquitin ligase complex, the CBF3 complex that binds centromeric DNA [[cite:PUB00006069]], and the RAVE complex that regulates assembly of the V-ATPase [[cite:PUB00067735]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
GO term | Namespace | Name | Definition | Relationships |
---|---|---|---|---|
Biological process | Ubiquitin-dependent protein catabolic process | The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein. |
Transcript | Name | Description | Predicted domains | Domain count |
---|---|---|---|---|
– | PREDICTED: SKP1-like protein 14-like [Cicer arietinum] gi|502088225|ref|XP_004488771.1| | 14 | ||
– | PREDICTED: SKP1-like protein 1A-like [Glycine max] gi|356496612|ref|XP_003517160.1| | 11 | ||
– | PREDICTED: SKP1-like protein 1A [Vitis vinifera] gi|225428047|ref|XP_002279232.1| | 7 | ||
– | PREDICTED: SKP1-like protein 14-like [Cicer arietinum] gi|502088225|ref|XP_004488771.1| | 14 | ||
– | PREDICTED: ethylene-responsive transcription factor 5-like [Glycine max] gi|356541103|ref|XP_003539022.1| | 20 | ||
– | PREDICTED: SKP1-like protein 14-like [Cicer arietinum] gi|502088225|ref|XP_004488771.1| | 14 | ||
– | PREDICTED: SKP1-like protein 21-like [Glycine max] gi|356531993|ref|XP_003534559.1| | 12 | ||
– | SKP1 component [Medicago truncatula] gi|124359727|gb|ABD32817.2| | 14 | ||
– | PREDICTED: SKP1-like protein 21-like [Glycine max] gi|356520400|ref|XP_003528850.1| | 14 | ||
– | PREDICTED: SKP1-like protein 1B isoform 2 [Vitis vinifera] gi|225457883|ref|XP_002270061.1| | 13 | ||
– | PREDICTED: SKP1-like protein 1A-like [Glycine max] gi|356496612|ref|XP_003517160.1| | 13 | ||
– | Skp1/Ask1-like protein [Zantedeschia hybrid cultivar] gi|47176688|gb|AAT12490.1| | 13 | ||
– | NAC domain protein IPR003441 [Medicago truncatula] gi|357494187|ref|XP_003617382.1| | 13 | ||
– | PREDICTED: transcription elongation factor B polypeptide 1 [Vitis vinifera] gi|225434792|ref|XP_002282124.1| | 8 | ||
– | PREDICTED: cullin-1-like isoform X1 [Cicer arietinum] gi|502151109|ref|XP_004508282.1| | 16 | ||
– | 10 | |||
– | PREDICTED: SKP1-like protein 1A-like [Glycine max] gi|356496612|ref|XP_003517160.1| | 8 | ||
– | PREDICTED: SKP1-like protein 1A-like [Glycine max] gi|356496612|ref|XP_003517160.1| | 13 | ||
– | PREDICTED: SKP1-like protein 1A [Vitis vinifera] gi|225428047|ref|XP_002279232.1| | 13 | ||
– | PREDICTED: SKP1-like protein 1A [Vitis vinifera] gi|225428047|ref|XP_002279232.1| | 13 | ||
– | LOB domain family protein; TAIR: AT2G25700.1 SKP1-like 3; Swiss-Prot: sp|Q9SL93|ASK3_ARATH SKP1-like protein 3; TrEMBL-Plants: tr|I3SSE0|I3SSE0_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0048300_LC | 15 | ||
– | SKP1 family protein; TAIR: AT3G61415.1 SKP1-like 21; Swiss-Prot: sp|Q8LF97|ASK21_ARATH SKP1-like protein 21; TrEMBL-Plants: tr|I1L6J4|I1L6J4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0477300 | 14 | ||
– | SKP1-like protein; TAIR: AT1G75950.1 S phase kinase-associated protein 1; Swiss-Prot: sp|Q39255|SKP1A_ARATH SKP1-like protein 1A; TrEMBL-Plants: tr|T2DMS9|T2DMS9_PHAVU SKP1-like protein; Found in the gene: LotjaGi2g1v0297400 | 16 | ||
– | SKP1-like protein; TAIR: AT1G75950.1 S phase kinase-associated protein 1; Swiss-Prot: sp|Q39255|SKP1A_ARATH SKP1-like protein 1A; TrEMBL-Plants: tr|I3SWX0|I3SWX0_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0379100 | 16 | ||
– | SKP1-like protein; TAIR: AT4G35920.1 PLAC8 family protein; Swiss-Prot: sp|B6SJQ0|CNR13_MAIZE Cell number regulator 13; TrEMBL-Plants: tr|I1J8I6|I1J8I6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0379100 | 21 | ||
– | SKP1-like protein; TAIR: AT1G75950.1 S phase kinase-associated protein 1; Swiss-Prot: sp|Q39255|SKP1A_ARATH SKP1-like protein 1A; TrEMBL-Plants: tr|I3SWX0|I3SWX0_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0379100 | 10 | ||
– | Ethylene-responsive transcription factor, putative; TAIR: AT5G47230.1 ethylene responsive element binding factor 5; Swiss-Prot: sp|O80341|EF102_ARATH Ethylene-responsive transcription factor 5; TrEMBL-Plants: tr|I1LGT2|I1LGT2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0299300_LC | 22 | ||
– | SKP1; TAIR: AT1G20140.1 SKP1-like 4; Swiss-Prot: sp|Q9LNT9|ASK4_ARATH SKP1-like protein 4; TrEMBL-Plants: tr|A0A1J7H518|A0A1J7H518_LUPAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0344100 | 16 | ||
– | SKP1; TAIR: AT2G03170.1 SKP1-like 14; Swiss-Prot: sp|O81057|ASK14_ARATH SKP1-like protein 14; TrEMBL-Plants: tr|I3SE65|I3SE65_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0344200_LC | 12 | ||
– | SKP1 family protein; TAIR: AT3G61415.1 SKP1-like 21; Swiss-Prot: sp|Q8LF97|ASK21_ARATH SKP1-like protein 21; TrEMBL-Plants: tr|A0A0S3SZ27|A0A0S3SZ27_PHAAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0384100 | 16 | ||
– | SKP1 family protein; TAIR: AT3G61415.1 SKP1-like 21; Swiss-Prot: sp|Q8LF97|ASK21_ARATH SKP1-like protein 21; TrEMBL-Plants: tr|I1KI94|I1KI94_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0384100 | 14 | ||
– | SKP1 family protein; TAIR: AT3G61415.1 SKP1-like 21; Swiss-Prot: sp|Q8LF97|ASK21_ARATH SKP1-like protein 21; TrEMBL-Plants: tr|I1KI94|I1KI94_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0384100 | 14 | ||
– | SKP1 family protein; TAIR: AT3G61415.1 SKP1-like 21; Swiss-Prot: sp|Q8LF97|ASK21_ARATH SKP1-like protein 21; TrEMBL-Plants: tr|K7KC10|K7KC10_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0384100 | 16 | ||
– | SKP1 family protein; TAIR: AT2G45950.1 SKP1-like 20; Swiss-Prot: sp|Q8LF97|ASK21_ARATH SKP1-like protein 21; TrEMBL-Plants: tr|I1KI94|I1KI94_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0384100 | 14 | ||
– | SKP1 family protein; TAIR: AT3G61415.2 SKP1-like 21; Swiss-Prot: sp|Q8LF97|ASK21_ARATH SKP1-like protein 21; TrEMBL-Plants: tr|I1KI94|I1KI94_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0384100 | 14 | ||
– | Transcription elongation factor B polypeptide 1; TAIR: AT5G59140.1 BTB/POZ domain-containing protein; Swiss-Prot: sp|Q2KII4|ELOC_BOVIN Elongin-C; TrEMBL-Plants: tr|A0A0S3SG76|A0A0S3SG76_PHAAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0491300 | 11 | ||
– | Transcription elongation factor B polypeptide 1; TAIR: AT5G59140.1 BTB/POZ domain-containing protein; Swiss-Prot: sp|Q2KII4|ELOC_BOVIN Elongin-C; TrEMBL-Plants: tr|A0A0S3SG76|A0A0S3SG76_PHAAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0491300 | 11 | ||
– | Transcription elongation factor B polypeptide 1; TAIR: AT5G59140.1 BTB/POZ domain-containing protein; Swiss-Prot: sp|Q2KII4|ELOC_BOVIN Elongin-C; TrEMBL-Plants: tr|A0A0S3SG76|A0A0S3SG76_PHAAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0491300 | 11 | ||
– | SKP1-like protein; TAIR: AT1G75950.1 S phase kinase-associated protein 1; Swiss-Prot: sp|Q39255|SKP1A_ARATH SKP1-like protein 1A; TrEMBL-Plants: tr|A0A1J7G3F5|A0A1J7G3F5_LUPAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0131700 | 16 | ||
– | SKP1-like protein; TAIR: AT1G75950.1 S phase kinase-associated protein 1; Swiss-Prot: sp|Q39255|SKP1A_ARATH SKP1-like protein 1A; TrEMBL-Plants: tr|F6GZT1|F6GZT1_VITVI Putative uncharacterized protein; Found in the gene: LotjaGi4g1v0232700_LC | 22 | ||
– | Cullin 1, putative; TAIR: AT4G02570.1 cullin 1; Swiss-Prot: sp|Q94AH6|CUL1_ARATH Cullin-1; TrEMBL-Plants: tr|I3SL73|I3SL73_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0343500 | 27 | ||
– | Cullin 1, putative; TAIR: AT4G02570.1 cullin 1; Swiss-Prot: sp|Q94AH6|CUL1_ARATH Cullin-1; TrEMBL-Plants: tr|I3SL73|I3SL73_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0343500 | 19 | ||
– | Cullin 1, putative; TAIR: AT4G02570.1 cullin 1; Swiss-Prot: sp|Q94AH6|CUL1_ARATH Cullin-1; TrEMBL-Plants: tr|I3SL73|I3SL73_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0344000 | 17 | ||
– | Cullin 1, putative; TAIR: AT4G02570.1 cullin 1; Swiss-Prot: sp|Q94AH6|CUL1_ARATH Cullin-1; TrEMBL-Plants: tr|I3SKE1|I3SKE1_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0344100 | 17 | ||
– | Cullin 1, putative; TAIR: AT4G02570.1 cullin 1; Swiss-Prot: sp|Q94AH6|CUL1_ARATH Cullin-1; TrEMBL-Plants: tr|I3SKE1|I3SKE1_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0344100 | 17 | ||
– | Cullin 1, putative; TAIR: AT4G02570.1 cullin 1; Swiss-Prot: sp|Q94AH6|CUL1_ARATH Cullin-1; TrEMBL-Plants: tr|I3SKE1|I3SKE1_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0344200 | 19 | ||
– | Cullin 1, putative; TAIR: AT4G02570.1 cullin 1; Swiss-Prot: sp|Q94AH6|CUL1_ARATH Cullin-1; TrEMBL-Plants: tr|I3SKE1|I3SKE1_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0344200 | 19 | ||
– | Cullin 1, putative; TAIR: AT4G02570.1 cullin 1; Swiss-Prot: sp|Q94AH6|CUL1_ARATH Cullin-1; TrEMBL-Plants: tr|I3SKE1|I3SKE1_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0344200 | 19 | ||
– | SKP1-like protein; TAIR: AT1G75950.1 S phase kinase-associated protein 1; Swiss-Prot: sp|Q39255|SKP1A_ARATH SKP1-like protein 1A; TrEMBL-Plants: tr|I3SES0|I3SES0_LOTJA Uncharacterized protein; Found in the gene: LotjaGi5g1v0006400 | 16 | ||
– | SKP1-like protein; TAIR: AT2G25700.1 SKP1-like 3; Swiss-Prot: sp|Q9SL93|ASK3_ARATH SKP1-like protein 3; TrEMBL-Plants: tr|A0A076JVB0|A0A076JVB0_9ROSA S-phase kinase-associated protein 1-like protein 3; Found in the gene: LotjaGi5g1v0348400 | 16 | ||
– | SKP1-like protein; TAIR: AT2G25700.1 SKP1-like 3; Swiss-Prot: sp|Q9SL93|ASK3_ARATH SKP1-like protein 3; TrEMBL-Plants: tr|A0A076JVB0|A0A076JVB0_9ROSA S-phase kinase-associated protein 1-like protein 3; Found in the gene: LotjaGi5g1v0348500 | 16 |
A list of co-occurring predicted domains within the L. japonicus gene space:
Predicted domain | Source | Observations | Saturation (%) |
---|---|---|---|
cd18322 | CDD | 1 | 1.96 |