Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message

IPR040040

Source: InterPro

Description

IPR040040 is a Autophagy-related protein 11.

<p>Autophagy-related protein 11 (ATG11; also known as cytoplasm to vacuole targeting protein 9) is required for transport of proteins from the cytosol to the vacuole [[cite:PUB00090447], [cite:PUB00044156]], including whole mitochondria for autophagic digestion (mitophagy) in the autophagosome during starvation [[cite:PUB00090448]]. It also acts as the scaffold that recruit ATG proteins to the pre-autophagosome [[cite:PUB00090449]]. The orthologue in mammals is known as RB1-inducible coiled-coil protein 1 (RB1CC1) [[cite:PUB00090450]]; the orthologue in Schizosaccharomyces pombe is Taz1-interacting factor 1 (taf1) [[cite:PUB00044913]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0000045
Biological process Autophagosome assembly The formation of a double membrane-bounded structure, the autophagosome, that occurs when a specialized membrane sac, called the isolation membrane, starts to enclose a portion of the cytoplasm.
Subterm of
GO:0000422
Biological process Autophagy of mitochondrion The autophagic process in which mitochondria are delivered to the vacuole and degraded in response to changing cellular conditions.
Subterm of

Associated Lotus transcripts 2

Transcript Name Description Predicted domains Domain count
LotjaGi4g1v0290300.1
– Autophagy-related protein 11; TAIR: AT4G30790.1 autophagy-like protein; Swiss-Prot: sp|Q9SUG7|ATG11_ARATH Autophagy-related protein 11; TrEMBL-Plants: tr|I1JGS5|I1JGS5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0290300
Domains
9
LotjaGi4g1v0290300.2
– Autophagy-related protein 11; TAIR: AT4G30790.1 autophagy-like protein; Swiss-Prot: sp|Q9SUG7|ATG11_ARATH Autophagy-related protein 11; TrEMBL-Plants: tr|I1JGS5|I1JGS5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0290300
Domains
9

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 50.00