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IPR040357

Source: InterPro

Description

IPR040357 is a Vma22/CCDC115.

<p>This entry includes Vma22 from yeasts and CCDC115 from animals. Vma22 is an endoplasmic reticulum-associated protein required for V-ATPase activity [[cite:PUB00090848], [cite:PUB00103834]]. CCDC115 is an accessory component of the proton-transporting vacuolar (V)-ATPase protein pump involved in intracellular iron homeostasis [[cite:PUB00090849]]. Mutations of CCDC115 have been found in patients affected by congenital disorders of glycosylation [[cite:PUB00103834]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0070072
Biological process Vacuolar proton-transporting V-type ATPase complex assembly The aggregation, arrangement and bonding together of a vacuolar proton-transporting V-type ATPase complex, proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across the vacuolar membrane.
Subterm of

Associated Lotus transcripts 2

Transcript Name Description Predicted domains Domain count
LotjaGi1g1v0567300.1
– Coiled-coil domain-containing protein 115 family; TAIR: AT1G20770.1 coiled-coil protein; Swiss-Prot: sp|Q5EAR6|CC115_DANRE Coiled-coil domain-containing protein 115; TrEMBL-Plants: tr|I3SFT0|I3SFT0_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0567300
Domains
2
LotjaGi1g1v0567300.2
– Coiled-coil domain-containing protein 115 family; TAIR: AT1G20770.1 coiled-coil protein; Swiss-Prot: sp|Q5EAR6|CC115_DANRE Coiled-coil domain-containing protein 115; TrEMBL-Plants: tr|I3SFT0|I3SFT0_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0567300
Domains
2

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
PTHR31996 PANTHER 1 50.00