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IPR041174 is a KRR1 small subunit processome component, first KH domain.
<p>This entry represents the first K homology domain (KH1) in the KRR1 and Dim2 (Pno1) proteins.</p> <p>Krr1 and Dim2 are structurally related ribosomal assembly factors, present on the 90S pre-ribosome [[cite:PUB00094299]]. They both belong to the family of RNA binding domains that contain K homology (KH) domains. Dim2 and Krr1 each contain two sequential KH domains (KH1 and KH2), but the N and C-terminal extensions differ between the two proteins [[cite:PUB00094299]]. The two KH domains are evident in the structure of KKr1 from Saccharomyces Cerevisiae [[cite:PUB00091469]].</p> <p>The KH1 domains in Krr1 and Dim2 lack the typical GXXG RNA binding motif and are involved, instead, in protein-protein interactions. The KH1 domain in Krr1 interacts with the nucleolar assembly factor Kri1 and the KH1 domain of Dim2 interacts with the endonuclease Nob1 [[cite:PUB00094299]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | KRR1 small subunit processome component; TAIR: AT5G08420.1 RNA-binding KH domain-containing protein; Swiss-Prot: sp|O74777|KRR1_SCHPO KRR1 small subunit processome component homolog; TrEMBL-Plants: tr|I1JIP3|I1JIP3_SOYBN KRR1 small subunit processome component; Found in the gene: LotjaGi1g1v0058400 | 9 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 100.00 |