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IPR041499 is a Transcription factor IIIC subunit Tfc1/Sfc1, triple barrel domain.
<p>TFIIIC1 is a multisubunit DNA binding factor that serves as a dynamic platform for assembly of pre-initiation complexes on class III genes. This entry represents the N-terminal triple barrel domain of the Tfc1/Sfc1 subunit. Tfc1/Sfc1 holds a key position in TFIIIC, exerting both upstream and downstream influence on the TFIIIC-DNA complex by rendering the complex more stable. Once bound to tDNA-intragenic promoter elements, TFIIIC directs the assembly of TFIIIB on the DNA, which in turn recruits the RNA polymerase III (pol III) and activates multiple rounds of transcription [[cite:PUB00045150]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | General transcription factor 3C polypeptide 5; TAIR: AT3G49410.1 Transcription factor IIIC, subunit 5; Swiss-Prot: sp|Q9Y5Q8|TF3C5_HUMAN General transcription factor 3C polypeptide 5; TrEMBL-Plants: tr|I1LI80|I1LI80_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0357200 | 10 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 100.00 |