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PF01073

Description

3-beta hydroxysteroid dehydrogenase/isomerase family

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Molecular function 3-beta-hydroxy-delta5-steroid dehydrogenase activity Catalysis of the reaction: a 3-beta-hydroxy-delta(5)-steroid + NAD+ = a 3-oxo-delta(5)-steroid + NADH + H(+).
Biological process Steroid biosynthetic process The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification.
Molecular function Oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.
Biological process Oxidation-reduction process A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.

Associated Lotus transcripts 16

Transcript Name Description Predicted domains Domain count
PREDICTED: 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 3-like [Glycine max] gi|356544508|ref|XP_003540692.1| 14
PREDICTED: cinnamoyl-CoA reductase 1-like [Cicer arietinum] gi|502129455|ref|XP_004500311.1| 7
PREDICTED: cinnamoyl-CoA reductase 1-like [Cicer arietinum] gi|502144229|ref|XP_004505624.1| 7
8
PREDICTED: 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 2-like [Cicer arietinum] gi|502132542|ref|XP_004501411.1| 7
Dihydroflavonol-4-reductase [Medicago truncatula] gi|357448325|ref|XP_003594438.1| 7
PREDICTED: 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 3-like [Glycine max] gi|356544508|ref|XP_003540692.1| 14
PREDICTED: cinnamoyl-CoA reductase 1-like [Cicer arietinum] gi|502144229|ref|XP_004505624.1| 7
PREDICTED: short-chain dehydrogenase/reductase family 42E member 1-like [Glycine max] gi|356553309|ref|XP_003544999.1| 13
Vestitone reductase [Medicago sativa] gi|973249|gb|AAB41550.1| 7
Reticulon-like protein; TAIR: AT2G26260.1 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 2; Swiss-Prot: sp|Q67ZE1|HSDD2_ARATH 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 2; TrEMBL-Plants: tr|G7J951|G7J951_MEDTR Reticulon-like protein; Found in the gene: LotjaGi1g1v0372600 14
Reticulon-like protein; TAIR: AT2G26260.1 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 2; Swiss-Prot: sp|Q67ZE1|HSDD2_ARATH 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 2; TrEMBL-Plants: tr|G7J951|G7J951_MEDTR Reticulon-like protein; Found in the gene: LotjaGi1g1v0372600 14
Reticulon-like protein; TAIR: AT2G26260.1 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 2; Swiss-Prot: sp|Q67ZE1|HSDD2_ARATH 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 2; TrEMBL-Plants: tr|G7J951|G7J951_MEDTR Reticulon-like protein; Found in the gene: LotjaGi1g1v0372600 14
Reticulon-like protein; TAIR: AT2G43420.1 3-beta hydroxysteroid dehydrogenase/isomerase family protein; Swiss-Prot: sp|A9X4U2|HSDD3_ARATH 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 3; TrEMBL-Plants: tr|K7LT52|K7LT52_SOYBN Reticulon-like protein; Found in the gene: LotjaGi3g1v0500400 14
Cinnamyl alcohol dehydrogenase; TAIR: AT1G51410.1 NAD(P)-binding Rossmann-fold superfamily protein; Swiss-Prot: sp|Q500U8|TKPR1_ARATH Tetraketide alpha-pyrone reductase 1; TrEMBL-Plants: tr|I3T4I3|I3T4I3_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0536900 8
Hydroxysteroid dehydrogenase 4; TAIR: AT2G33630.1 NAD(P)-binding Rossmann-fold superfamily protein; Swiss-Prot: sp|Q4R7R1|D42E1_MACFA Short-chain dehydrogenase/reductase family 42E member 1; TrEMBL-Plants: tr|I3S981|I3S981_LOTJA Uncharacterized protein; Found in the gene: LotjaGi5g1v0000700 18

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
TRANSMEMBRANE Phobius 1 6.25