Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message

GO:0000380

Overview

Field Value
Namespace Biological process
Short description Alternative mRNA splicing, via spliceosome
Full defintion The process of generating multiple mRNA molecules from a given set of exons by differential use of exons from the primary transcript(s) to form multiple mature mRNAs that vary in their exon composition.
Subterm of

Relationships

The relationship of GO:0000380 with other GO terms.

Relationship type GO terms
Is a
Regulates n.a.
Part of n.a.
Positively regulates n.a.
Negatively regulates n.a.

Ancestor tree

A force layout showing the ancestor tree for GO:0000380, and its immediate children. If you wish to explore the tree dynamically, please use the GO Explorer.

  • Drag and drop nodes to manually position (i.e. fix) them
  • Double click on a node to unfix the node
  • Press Alt and double click to visit the page containing further details of a GO term
  • Right clicking on a node will reveal a context menu

Controls

Force layout

Every force layout is different—we have picked a set of parameters which suits most GO ancestor tree chart well. If you mess something up—don't worry: hitting the "reset view" button above will reset the chart to its default layout.

Additional data

This table contains additional metadata associated with the GO entry's definition field.

Field Value
GOCkrc
PMID
Alternative pre-mRNA splicing and proteome expansion in metazoans.
Nature. ; 418 (6894): 236–43.PMID: 12110900

The protein coding sequences of most eukaryotic messenger RNA precursors (pre-mRNAs) are interrupted by non-coding sequences called introns. Pre-mRNA splicing is the process by which introns are removed and the protein coding elements assembled into mature mRNAs. Alternative pre-mRNA splicing selectively joins different protein coding elements to form mRNAs that encode proteins with distinct functions, and is therefore an important source of protein diversity. The elaboration of this mechanism may have had a significant role in the expansion of metazoan proteomes during evolution.

Associated Lotus transcripts 1

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

Transcript Name Description GO terms GO count
Arginine/serine-rich coiled coil protein; TAIR: AT3G48120.1 serine/arginine-rich splicing factor; Swiss-Prot: sp|Q9AS36|CCL11_ORYSJ Cyclin-L1-1; TrEMBL-Plants: tr|A0A1J7HF63|A0A1J7HF63_LUPAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0236700_LC 2

Co-occuring GO terms 1

A list of co-occurring GO terms within the L. japonicus gene space:

GO term Namespace Name Observations Saturation (%)
Biological process MRNA splicing, via spliceosome 1 100.00