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GO:0003774

View this GO term in other databases

Overview

Field Value
Namespace Molecular function
Short description Motor activity
Full defintion Catalysis of the generation of force resulting either in movement along a microfilament or microtubule, or in torque resulting in membrane scission, coupled to the hydrolysis of a nucleoside triphosphate.
Subterm of

Relationships

The relationship of GO:0003774 with other GO terms.

Relationship type GO terms
Is a
Regulates n.a.
Part of n.a.
Positively regulates n.a.
Negatively regulates n.a.

Ancestor tree

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Additional data

This table contains additional metadata associated with the GO entry's definition field.

Field Value
GOCvw
ISBN

· ISBN: 0815316194

, · pages

PMID
GTPase activity of dynamin and resulting conformation change are essential for endocytosis.Marks B, Stowell MH, Vallis Y, Mills IG, Gibson A, Hopkins CR, McMahon HT
Nature. 2001 Mar 8; 410 (6825): 231–5.PMID: 11242086

Dynamin is a large GTPase with a relative molecular mass of 96,000 (Mr 96K) that is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Although its function is apparently essential for scission of newly formed vesicles from the plasma membrane, the nature of dynamin's role in the scission process is still unclear. It has been proposed that dynamin is a regulator (similar to classical G proteins) of downstream effectors. Here we report the analysis of several point mutants of dynamin's GTPase effector (GED) and GTPase domains. We show that oligomerization and GTP binding alone, by dynamin, are not sufficient for endocytosis in vivo. Rather, efficient GTP hydrolysis and an associated conformational change are also required. These data argue that dynamin has a mechanochemical function in vesicle scission.

Associated Lotus transcripts 59

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

Transcript Name Description GO terms GO count
Lj0g3v0047839.3
– PREDICTED: myosin-J heavy chain-like [Cicer arietinum] gi|502123437|ref|XP_004498109.1|
GO terms
3
Lj0g3v0085549.1
– PREDICTED: myosin-J heavy chain-like [Glycine max] gi|356576949|ref|XP_003556592.1|
GO terms
3
Lj0g3v0296779.1
– PREDICTED: myosin-Va-like [Glycine max] gi|356530241|ref|XP_003533691.1|
GO terms
3
Lj1g3v0934400.1
– PREDICTED: myosin IB heavy chain-like [Cicer arietinum] gi|502136227|ref|XP_004502607.1|
GO terms
2
Lj1g3v2625950.1
– Myosin head, motor region [Medicago truncatula] gi|124360174|gb|ABN08187.1|
GO terms
3
Lj1g3v4998410.1
– Myosin heavy chain PCR1 - Arabidopsis thaliana (fragment)] gi|1076352|pir||S51820
GO terms
3
Lj4g3v2178110.2
– PREDICTED: unconventional myosin-Va-like [Cucumis sativus] gi|449452532|ref|XP_004144013.1|
GO terms
3
LotjaGi1g1v0170800.1
– Myosin heavy chain-like protein; TAIR: AT5G53310.1 myosin heavy chain-like protein; Swiss-Prot: sp|P34092|MYOB_DICDI Myosin IB heavy chain; TrEMBL-Plants: tr|A0A151R760|A0A151R760_CAJCA Myosin IB heavy chain; Found in the gene: LotjaGi1g1v0170800
GO terms
2
LotjaGi1g1v0783500.1
– Myosin; TAIR: AT1G54560.1 Myosin family protein with Dil domain-containing protein; Swiss-Prot: sp|F4HWY6|MYO11_ARATH Myosin-11; TrEMBL-Plants: tr|A0A072U4E6|A0A072U4E6_MEDTR DIL domain myosin family protein; Found in the gene: LotjaGi1g1v0783500
GO terms
3
LotjaGi1g1v0783500.2
– Myosin family protein, putative, expressed; TAIR: AT1G54560.1 Myosin family protein with Dil domain-containing protein; Swiss-Prot: sp|F4HWY6|MYO11_ARATH Myosin-11; TrEMBL-Plants: tr|A0A072U4E6|A0A072U4E6_MEDTR DIL domain myosin family protein; Found in the gene: LotjaGi1g1v0783500
GO terms
3
LotjaGi1g1v0783500.3
– Myosin family protein, putative, expressed; TAIR: AT1G54560.1 Myosin family protein with Dil domain-containing protein; Swiss-Prot: sp|F4HWY6|MYO11_ARATH Myosin-11; TrEMBL-Plants: tr|A0A072U4E6|A0A072U4E6_MEDTR DIL domain myosin family protein; Found in the gene: LotjaGi1g1v0783500
GO terms
3
LotjaGi1g1v0783500.4
– Myosin family protein, putative, expressed; TAIR: AT1G54560.2 Myosin family protein with Dil domain-containing protein; Swiss-Prot: sp|F4HWY6|MYO11_ARATH Myosin-11; TrEMBL-Plants: tr|A0A072U4E6|A0A072U4E6_MEDTR DIL domain myosin family protein; Found in the gene: LotjaGi1g1v0783500
GO terms
3
LotjaGi1g1v0783500.5
– Myosin family protein, putative, expressed; TAIR: AT1G54560.1 Myosin family protein with Dil domain-containing protein; Swiss-Prot: sp|F4HWY6|MYO11_ARATH Myosin-11; TrEMBL-Plants: tr|A0A0B2Q046|A0A0B2Q046_GLYSO Myosin-J heavy chain; Found in the gene: LotjaGi1g1v0783500
GO terms
3
LotjaGi1g1v0783500.6
– Myosin family protein, putative, expressed; TAIR: AT1G54560.1 Myosin family protein with Dil domain-containing protein; Swiss-Prot: sp|F4HWY6|MYO11_ARATH Myosin-11; TrEMBL-Plants: tr|A0A072U4E6|A0A072U4E6_MEDTR DIL domain myosin family protein; Found in the gene: LotjaGi1g1v0783500
GO terms
3
LotjaGi1g1v0783500.7
– Myosin family protein, putative, expressed; TAIR: AT1G54560.2 Myosin family protein with Dil domain-containing protein; Swiss-Prot: sp|F4HWY6|MYO11_ARATH Myosin-11; TrEMBL-Plants: tr|A0A072U4E6|A0A072U4E6_MEDTR DIL domain myosin family protein; Found in the gene: LotjaGi1g1v0783500
GO terms
3
LotjaGi2g1v0020800.1
– Myosin; TAIR: AT1G04160.1 myosin XI B; Swiss-Prot: sp|F4I460|MYO8_ARATH Myosin-8; TrEMBL-Plants: tr|A0A0R0E5G3|A0A0R0E5G3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0020800
GO terms
3
LotjaGi2g1v0020800.2
– Myosin; TAIR: AT1G04600.1 myosin XI A; Swiss-Prot: sp|F4I5Q6|MYO7_ARATH Myosin-7; TrEMBL-Plants: tr|A0A072VH49|A0A072VH49_MEDTR Myosin heavy chain; Found in the gene: LotjaGi2g1v0020800
GO terms
4
LotjaGi2g1v0024000.1
– Myosin-related family protein; TAIR: AT3G19960.1 myosin 1; Swiss-Prot: sp|Q9LHE9|MYO1_ARATH Myosin-1; TrEMBL-Plants: tr|A0A0S3T0K8|A0A0S3T0K8_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0024000
GO terms
3
LotjaGi2g1v0024000.2
– Myosin-related family protein; TAIR: AT3G19960.1 myosin 1; Swiss-Prot: sp|Q9LHE9|MYO1_ARATH Myosin-1; TrEMBL-Plants: tr|A0A0S3T0K8|A0A0S3T0K8_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0024000
GO terms
3
LotjaGi2g1v0024000.3
– Myosin-related family protein; TAIR: AT3G19960.1 myosin 1; Swiss-Prot: sp|Q9LHE9|MYO1_ARATH Myosin-1; TrEMBL-Plants: tr|I1NCW2|I1NCW2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0024000
GO terms
4
LotjaGi2g1v0024000.4
– Myosin-related family protein; TAIR: AT3G19960.1 myosin 1; Swiss-Prot: sp|Q9LHE9|MYO1_ARATH Myosin-1; TrEMBL-Plants: tr|A0A0S3T0K8|A0A0S3T0K8_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0024000
GO terms
3
LotjaGi2g1v0024000.5
– Myosin-related family protein; TAIR: AT3G19960.1 myosin 1; Swiss-Prot: sp|Q9LHE9|MYO1_ARATH Myosin-1; TrEMBL-Plants: tr|A0A0S3T0K8|A0A0S3T0K8_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0024000
GO terms
3
LotjaGi2g1v0024000.6
– Myosin-related family protein; TAIR: AT3G19960.1 myosin 1; Swiss-Prot: sp|Q9LHE9|MYO1_ARATH Myosin-1; TrEMBL-Plants: tr|A0A0S3T0K8|A0A0S3T0K8_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0024000
GO terms
3
LotjaGi2g1v0024000.7
– Myosin-related family protein; TAIR: AT3G19960.1 myosin 1; Swiss-Prot: sp|Q9LHE9|MYO1_ARATH Myosin-1; TrEMBL-Plants: tr|A0A0S3T0K8|A0A0S3T0K8_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0024000
GO terms
3
LotjaGi2g1v0024000.8
– Myosin-related family protein; TAIR: AT3G19960.1 myosin 1; Swiss-Prot: sp|Q9LHE9|MYO1_ARATH Myosin-1; TrEMBL-Plants: tr|A0A0S3T0K8|A0A0S3T0K8_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0024000
GO terms
3
LotjaGi3g1v0078600.1
– Myosin-related family protein; TAIR: AT5G54280.2 myosin 2; Swiss-Prot: sp|F4K0A6|MYO2_ARATH Myosin-2; TrEMBL-Plants: tr|A0A0B2R755|A0A0B2R755_GLYSO Myosin-J heavy chain; Found in the gene: LotjaGi3g1v0078600
GO terms
3
LotjaGi3g1v0078600.2
– Myosin-related family protein; TAIR: AT5G54280.2 myosin 2; Swiss-Prot: sp|F4K0A6|MYO2_ARATH Myosin-2; TrEMBL-Plants: tr|A0A0B2R755|A0A0B2R755_GLYSO Myosin-J heavy chain; Found in the gene: LotjaGi3g1v0078600
GO terms
3
LotjaGi3g1v0129700.1
– Myosin family protein, putative, expressed; TAIR: AT2G31900.1 myosin-like protein XIF; Swiss-Prot: sp|F4IRU3|MYO12_ARATH Myosin-12; TrEMBL-Plants: tr|V7BT17|V7BT17_PHAVU Uncharacterized protein; Found in the gene: LotjaGi3g1v0129700
GO terms
3
LotjaGi3g1v0129700.2
– Myosin family protein, putative, expressed; TAIR: AT2G31900.1 myosin-like protein XIF; Swiss-Prot: sp|F4IRU3|MYO12_ARATH Myosin-12; TrEMBL-Plants: tr|A0A0S3SJT2|A0A0S3SJT2_PHAAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0129700
GO terms
3
LotjaGi3g1v0129700.3
– Myosin family protein, putative, expressed; TAIR: AT2G31900.1 myosin-like protein XIF; Swiss-Prot: sp|F4IRU3|MYO12_ARATH Myosin-12; TrEMBL-Plants: tr|V7BT17|V7BT17_PHAVU Uncharacterized protein; Found in the gene: LotjaGi3g1v0129700
GO terms
3
LotjaGi3g1v0129700.4
– Myosin family protein, putative, expressed; TAIR: AT2G31900.1 myosin-like protein XIF; Swiss-Prot: sp|F4IRU3|MYO12_ARATH Myosin-12; TrEMBL-Plants: tr|I1KTU1|I1KTU1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0129700
GO terms
3
LotjaGi3g1v0129700.5
– Myosin family protein, putative, expressed; TAIR: AT2G31900.1 myosin-like protein XIF; Swiss-Prot: sp|F4IRU3|MYO12_ARATH Myosin-12; TrEMBL-Plants: tr|V7BT17|V7BT17_PHAVU Uncharacterized protein; Found in the gene: LotjaGi3g1v0129700
GO terms
3
LotjaGi3g1v0129700.6
– Myosin family protein, putative, expressed; TAIR: AT2G31900.1 myosin-like protein XIF; Swiss-Prot: sp|F4IRU3|MYO12_ARATH Myosin-12; TrEMBL-Plants: tr|V7BT17|V7BT17_PHAVU Uncharacterized protein; Found in the gene: LotjaGi3g1v0129700
GO terms
3
LotjaGi3g1v0129700.7
– Myosin family protein, putative, expressed; TAIR: AT2G31900.1 myosin-like protein XIF; Swiss-Prot: sp|F4IRU3|MYO12_ARATH Myosin-12; TrEMBL-Plants: tr|A0A0B2S645|A0A0B2S645_GLYSO Myosin-J heavy chain; Found in the gene: LotjaGi3g1v0129700
GO terms
3
LotjaGi4g1v0328000.1
– Myosin; TAIR: AT5G20490.2 myosin family protein with Dil; Swiss-Prot: sp|F4K5J1|MYO17_ARATH Myosin-17; TrEMBL-Plants: tr|A0A072US24|A0A072US24_MEDTR DIL domain myosin family protein; Found in the gene: LotjaGi4g1v0328000
GO terms
3
LotjaGi4g1v0328000.2
– Myosin family protein, putative, expressed; TAIR: AT5G20490.3 myosin family protein with Dil; Swiss-Prot: sp|F4K5J1|MYO17_ARATH Myosin-17; TrEMBL-Plants: tr|A0A072US24|A0A072US24_MEDTR DIL domain myosin family protein; Found in the gene: LotjaGi4g1v0328000
GO terms
3
LotjaGi5g1v0045300.1
– Myosin; TAIR: AT4G33200.1 myosin; Swiss-Prot: sp|Q0WPU1|MYO15_ARATH Myosin-15; TrEMBL-Plants: tr|K7M5Y2|K7M5Y2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0045300
GO terms
3
LotjaGi5g1v0045300.2
– Myosin; TAIR: AT4G33200.1 myosin; Swiss-Prot: sp|Q0WPU1|MYO15_ARATH Myosin-15; TrEMBL-Plants: tr|K7M5Y2|K7M5Y2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0045300
GO terms
3
LotjaGi5g1v0045300.3
– Myosin; TAIR: AT4G33200.1 myosin; Swiss-Prot: sp|Q0WPU1|MYO15_ARATH Myosin-15; TrEMBL-Plants: tr|K7M5Y2|K7M5Y2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0045300
GO terms
3
LotjaGi5g1v0045300.4
– Myosin; TAIR: AT4G33200.1 myosin; Swiss-Prot: sp|Q0WPU1|MYO15_ARATH Myosin-15; TrEMBL-Plants: tr|K7M5Y2|K7M5Y2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0045300
GO terms
3
LotjaGi5g1v0151100.1
– Myosin; TAIR: AT5G43900.3 myosin 2; Swiss-Prot: sp|Q9LKB9|MYO6_ARATH Myosin-6; TrEMBL-Plants: tr|K7LHD6|K7LHD6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0151100
GO terms
3
LotjaGi5g1v0151100.2
– Myosin; TAIR: AT5G43900.3 myosin 2; Swiss-Prot: sp|Q9LKB9|MYO6_ARATH Myosin-6; TrEMBL-Plants: tr|K7LHD6|K7LHD6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0151100
GO terms
3
LotjaGi5g1v0151100.3
– Myosin; TAIR: AT5G43900.3 myosin 2; Swiss-Prot: sp|Q9LKB9|MYO6_ARATH Myosin-6; TrEMBL-Plants: tr|I1L8I7|I1L8I7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0151100
GO terms
3
LotjaGi5g1v0151100.4
– Myosin; TAIR: AT5G43900.2 myosin 2; Swiss-Prot: sp|Q9LKB9|MYO6_ARATH Myosin-6; TrEMBL-Plants: tr|A0A0R0HP80|A0A0R0HP80_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0151100
GO terms
3
LotjaGi5g1v0178200.1
– Myosin; TAIR: AT1G54560.2 Myosin family protein with Dil domain-containing protein; Swiss-Prot: sp|F4HWY6|MYO11_ARATH Myosin-11; TrEMBL-Plants: tr|A0A0R0GUH4|A0A0R0GUH4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0178200
GO terms
3
LotjaGi5g1v0178200.2
– Myosin; TAIR: AT1G54560.2 Myosin family protein with Dil domain-containing protein; Swiss-Prot: sp|F4HWY6|MYO11_ARATH Myosin-11; TrEMBL-Plants: tr|K7LZ94|K7LZ94_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0178200
GO terms
3
LotjaGi5g1v0178200.3
– Myosin; TAIR: AT1G54560.1 Myosin family protein with Dil domain-containing protein; Swiss-Prot: sp|F4HWY6|MYO11_ARATH Myosin-11; TrEMBL-Plants: tr|A0A0R0GUH4|A0A0R0GUH4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0178200
GO terms
3
LotjaGi5g1v0178200.4
– Myosin family protein, putative, expressed; TAIR: AT1G54560.1 Myosin family protein with Dil domain-containing protein; Swiss-Prot: sp|F4HWY6|MYO11_ARATH Myosin-11; TrEMBL-Plants: tr|K7LZ94|K7LZ94_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0178200
GO terms
3
LotjaGi5g1v0178200.5
– Myosin family protein, putative, expressed; TAIR: AT1G08730.2 Myosin family protein with Dil domain-containing protein; Swiss-Prot: sp|F4HXP9|MYO9_ARATH Myosin-9; TrEMBL-Plants: tr|A0A0R0GUH4|A0A0R0GUH4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0178200
GO terms
3
LotjaGi5g1v0178200.6
– Myosin family protein, putative, expressed; TAIR: AT1G54560.2 Myosin family protein with Dil domain-containing protein; Swiss-Prot: sp|F4HWY6|MYO11_ARATH Myosin-11; TrEMBL-Plants: tr|A0A0R0GUH4|A0A0R0GUH4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0178200
GO terms
3
LotjaGi5g1v0210600.1
– Myosin; TAIR: AT1G54560.2 Myosin family protein with Dil domain-containing protein; Swiss-Prot: sp|F4HWY6|MYO11_ARATH Myosin-11; TrEMBL-Plants: tr|I1NIS2|I1NIS2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0210600
GO terms
3
LotjaGi5g1v0210600.2
– Myosin family protein, putative, expressed; TAIR: AT1G54560.1 Myosin family protein with Dil domain-containing protein; Swiss-Prot: sp|F4HWY6|MYO11_ARATH Myosin-11; TrEMBL-Plants: tr|I1NIS2|I1NIS2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0210600
GO terms
3
LotjaGi5g1v0353200.1
– Myosin-related family protein; TAIR: AT3G19960.1 myosin 1; Swiss-Prot: sp|Q9LHE9|MYO1_ARATH Myosin-1; TrEMBL-Plants: tr|I1NF52|I1NF52_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0353200
GO terms
3
LotjaGi5g1v0353200.2
– Myosin-related family protein; TAIR: AT3G19960.1 myosin 1; Swiss-Prot: sp|Q9LHE9|MYO1_ARATH Myosin-1; TrEMBL-Plants: tr|I1NF52|I1NF52_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0353200
GO terms
3
LotjaGi5g1v0353200.3
– Myosin-related family protein; TAIR: AT3G19960.1 myosin 1; Swiss-Prot: sp|Q9LHE9|MYO1_ARATH Myosin-1; TrEMBL-Plants: tr|I1NF52|I1NF52_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0353200
GO terms
4
LotjaGi5g1v0353200.4
– Myosin-related family protein; TAIR: AT3G19960.1 myosin 1; Swiss-Prot: sp|Q9LHE9|MYO1_ARATH Myosin-1; TrEMBL-Plants: tr|I1NF52|I1NF52_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0353200
GO terms
3
LotjaGi5g1v0353200.5
– Myosin-related family protein; TAIR: AT3G19960.1 myosin 1; Swiss-Prot: sp|Q9LHE9|MYO1_ARATH Myosin-1; TrEMBL-Plants: tr|I1NF52|I1NF52_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0353200
GO terms
3
LotjaGi5g1v0353200.6
– Myosin-related family protein; TAIR: AT3G19960.1 myosin 1; Swiss-Prot: sp|Q9LHE9|MYO1_ARATH Myosin-1; TrEMBL-Plants: tr|I1NF52|I1NF52_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0353200
GO terms
3
LotjaGi5g1v0353200.7
– Myosin-related family protein; TAIR: AT3G19960.1 myosin 1; Swiss-Prot: sp|Q9LHE9|MYO1_ARATH Myosin-1; TrEMBL-Plants: tr|I1NF52|I1NF52_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0353200
GO terms
3

Co-occuring GO terms 1

A list of co-occurring GO terms within the L. japonicus gene space:

GO term Namespace Name Observations Saturation (%)
GO:0016459
Cellular component Myosin complex 1 1.69