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GO:0010264

View this GO term in other databases

Overview

Field Value
Namespace Biological process
Short description Myo-inositol hexakisphosphate biosynthetic process
Full defintion The chemical reactions and pathways resulting in the formation of phytic acid, myo-inositol hexakisphosphate, a regulator of intracellular signaling, a highly abundant animal anti-nutrient and a phosphate and mineral storage compound in plant seeds.
Subterm of

Relationships

The relationship of GO:0010264 with other GO terms.

Relationship type GO terms
Is a
Regulates n.a.
Part of n.a.
Positively regulates n.a.
Negatively regulates n.a.

Ancestor tree

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Additional data

This table contains additional metadata associated with the GO entry's definition field.

Field Value
CHEBI17401
PMID
Generation of phytate-free seeds in Arabidopsis through disruption of inositol polyphosphate kinases.Stevenson-Paulik J, Bastidas RJ, Chiou ST, Frye RA, York JD
Proc Natl Acad Sci U S A. 2005 Aug 30; 102 (35): 12612–7.PMID: 16107538

Phytate (inositol hexakisphosphate, IP6) is a regulator of intracellular signaling, a highly abundant animal antinutrient, and a phosphate store in plant seeds. Here, we report a requirement for inositol polyphosphate kinases, AtIPK1 and AtIPK2beta, for the later steps of phytate synthesis in Arabidopsis thaliana. Coincident disruption of these kinases nearly ablates seed phytate without accumulation of phytate precursors, increases seed-free phosphate by 10-fold, and has normal seed yield. Additionally, we find a requirement for inositol tetrakisphosphate (IP4)/inositol pentakisphosphate (IP5) 2-kinase activity in phosphate sensing and root hair elongation. Our results define a commercially viable strategy for the genetic engineering of phytate-free grain and provide insights into the role of inositol polyphosphate kinases in phosphate signaling biology.

Associated Lotus transcripts 2

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

Transcript Name Description GO terms GO count
Lj2g3v2256350.1
– 5-dehydro-2-deoxygluconokinase [Medicago truncatula] gi|357490699|ref|XP_003615637.1|
GO terms
3
LotjaGi1g1v0120500.1
– Kinase PfkB; TAIR: AT5G58730.1 pfkB-like carbohydrate kinase family protein; Swiss-Prot: sp|Q93Z01|MIK_ARATH Inositol 3-kinase; TrEMBL-Plants: tr|I1MBA8|I1MBA8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0120500
GO terms
3

Co-occuring GO terms 1

A list of co-occurring GO terms within the L. japonicus gene space:

GO term Namespace Name Observations Saturation (%)
GO:0019140
Molecular function Inositol 3-kinase activity 1 50.00