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Field | Value |
---|---|
Namespace | Cellular component |
Short description | Ribonuclease P complex |
Full defintion | A ribonucleoprotein complex that catalyzes cleavage of the leader sequence of precursor tRNAs (pre-tRNAs), generating the mature 5' end of tRNAs. |
Subterm of |
The relationship of GO:0030677 with other GO terms.
Relationship type | GO terms |
---|---|
Is a | |
Regulates | n.a. |
Part of | n.a. |
Positively regulates | n.a. |
Negatively regulates | n.a. |
A force layout showing the ancestor tree for GO:0030677, and its immediate children. If you wish to explore the tree dynamically, please use the GO Explorer.
This table contains additional metadata associated with the GO entry's definition field.
Field | Value |
---|---|
GOC | mah |
PMID | Eukaryotic ribonuclease P: a plurality of ribonucleoprotein enzymes. Annu Rev Biochem. 2002; 71 (): 165–89.PMID: 12045094 Ribonuclease P (RNase P) is an essential endonuclease that acts early in the tRNA biogenesis pathway. This enzyme catalyzes cleavage of the leader sequence of precursor tRNAs (pre-tRNAs), generating the mature 5' end of tRNAs. RNase P activities have been identified in Bacteria, Archaea, and Eucarya, as well as organelles. Most forms of RNase P are ribonucleoproteins, i.e., they consist of an essential RNA subunit and protein subunits, although the composition of the enzyme in mitochondria and chloroplasts is still under debate. The recent purification of the eukaryotic nuclear RNase P has demonstrated a significantly larger protein content compared to the bacterial enzyme. Moreover, emerging evidence suggests that the eukaryotic RNase P has evolved into at least two related nuclear enzymes with distinct functions, RNase P and RNase MRP. Here we review current information on RNase P, with emphasis on the composition, structure, and functions of the eukaryotic nuclear holoenzyme, and its relationship with RNase MRP. |
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
Transcript | Name | Description | GO terms | GO count |
---|---|---|---|---|
– | POP4-like protein [Arabidopsis thaliana] gi|334184895|ref|NP_001189739.1| | 4 | ||
– | 4 | |||
– | Ribonuclease P protein subunit p29 [Medicago truncatula] gi|357481161|ref|XP_003610866.1| | 4 | ||
– | Ribonuclease P protein subunit p29 [Medicago truncatula] gi|357481161|ref|XP_003610866.1| | 4 | ||
– | Ribonuclease P protein subunit p29 [Medicago truncatula] gi|357481161|ref|XP_003610866.1| | 4 | ||
– | Ribonuclease P protein subunit p29 [Medicago truncatula] gi|357481161|ref|XP_003610866.1| | 4 | ||
– | Ribonuclease P protein subunit p29; TAIR: AT2G43190.1 ribonuclease P family protein; Swiss-Prot: sp|Q9CR08|RPP29_MOUSE Ribonuclease P protein subunit p29; TrEMBL-Plants: tr|I1LG21|I1LG21_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0448500 | 5 | ||
– | Ribonuclease P protein subunit p29; TAIR: AT2G43190.1 ribonuclease P family protein; Swiss-Prot: sp|Q9CR08|RPP29_MOUSE Ribonuclease P protein subunit p29; TrEMBL-Plants: tr|I1LG21|I1LG21_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0448500 | 5 |
A list of co-occurring GO terms within the L. japonicus gene space:
GO term | Namespace | Name | Observations | Saturation (%) |
---|---|---|---|---|
Cellular component | Ribonuclease P complex | 1 | 12.50 |