Gene Ontology — View

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GO:0070985

Overview

Field	Value
Namespace	Cellular component
Short description	Transcription factor TFIIK complex
Full defintion	A transcription factor complex that forms part of the holo TFIIH complex. In Saccharomyces/human, TFIIK contains Ccl1p/Cyclin H, Tfb3p/MAT1 and Kin2p/CDK7.
Subterm of	GO:0044451 GO:0090575

Relationships

The relationship of GO:0070985 with other GO terms.

Relationship type	GO terms
Is a	GO:0044451 GO:0090575
Regulates	n.a.
Part of	GO:0005675
Positively regulates	n.a.
Negatively regulates	n.a.

Ancestor tree

A force layout showing the ancestor tree for GO:0070985, and its immediate children. If you wish to explore the tree dynamically, please use the GO Explorer.

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Additional data

This table contains additional metadata associated with the GO entry's definition field.

Field	Value
GOC	mah
PMID	TFIIH: when transcription met DNA repair.Compe E, Egly JM Nat Rev Mol Cell Biol. 2012 May 10; 13 (6): 343–54.PMID: 22572993 The transcription initiation factor TFIIH is a remarkable protein complex that has a fundamental role in the transcription of protein-coding genes as well as during the DNA nucleotide excision repair pathway. The detailed understanding of how TFIIH functions to coordinate these two processes is also providing an explanation for the phenotypes observed in patients who bear mutations in some of the TFIIH subunits. In this way, studies of TFIIH have revealed tight molecular connections between transcription and DNA repair and have helped to define the concept of 'transcription diseases'.

Field

Value

GOC

mah

PMID

TFIIH: when transcription met DNA repair.Compe E, Egly JM
Nat Rev Mol Cell Biol. 2012 May 10; 13 (6): 343–54.PMID: 22572993

The transcription initiation factor TFIIH is a remarkable protein complex that has a fundamental role in the transcription of protein-coding genes as well as during the DNA nucleotide excision repair pathway. The detailed understanding of how TFIIH functions to coordinate these two processes is also providing an explanation for the phenotypes observed in patients who bear mutations in some of the TFIIH subunits. In this way, studies of TFIIH have revealed tight molecular connections between transcription and DNA repair and have helped to define the concept of 'transcription diseases'.

Associated Lotus transcripts 1

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on April 27, 2020, while the GO metadata was last updated on April 27, 2020.

Transcript	Name	Description	GO terms	GO count
Lj0g3v0326469.1 View transcript LORE1 insertions in MG20 v3.0 Genome browser Expression Atlas (ExpAt)	–	PREDICTED: cyclin-H1-1 isoform 1 [Glycine max] gi\|356516489\|ref\|XP_003526926.1\|	GO terms View details of GO:0006351 View details of GO:0016538 View details of GO:0070985	3

Co-occuring GO terms 1

A list of co-occurring GO terms within the L. japonicus gene space:

GO term	Namespace	Name	Observations	Saturation (%)
GO:0070985 View details of GO:0070985 AmiGO InterPro QuickGO	Cellular component	Transcription factor TFIIK complex	1	100.00