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GO:0071013
Overview
| Field | Value |
|---|---|
| Namespace | Cellular component |
| Short description | Catalytic step 2 spliceosome |
| Full defintion | A spliceosomal complex that contains three snRNPs, including U5, bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the associated snRNPs. |
| Subterm of |
Relationships
The relationship of GO:0071013 with other GO terms.
| Relationship type | GO terms |
|---|---|
| Is a | |
| Regulates | n.a. |
| Part of | n.a. |
| Positively regulates | n.a. |
| Negatively regulates | n.a. |
Ancestor tree
A force layout showing the ancestor tree for GO:0071013, and its immediate children. If you wish to explore the tree dynamically, please use the GO Explorer.
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Additional data
This table contains additional metadata associated with the GO entry's definition field.
| Field | Value |
|---|---|
| GOC | mah |
| ISBN | |
| PMID | The spliceosome: design principles of a dynamic RNP machine. Cell. 2009 Feb 20; 136 (4): 701–18.PMID: 19239890 Ribonucleoproteins (RNPs) mediate key cellular functions such as gene expression and its regulation. Whereas most RNP enzymes are stable in composition and harbor preformed active sites, the spliceosome, which removes noncoding introns from precursor messenger RNAs (pre-mRNAs), follows fundamentally different strategies. In order to provide both accuracy to the recognition of reactive splice sites in the pre-mRNA and flexibility to the choice of splice sites during alternative splicing, the spliceosome exhibits exceptional compositional and structural dynamics that are exploited during substrate-dependent complex assembly, catalytic activation, and active site remodeling. |
Associated Lotus transcripts 3
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| Transcript | Name | Description | GO terms | GO count |
|---|---|---|---|---|
| – | Pre-mRNA-processing factor [Medicago truncatula] gi|357440851|ref|XP_003590703.1| | 2 | ||
| – | Transducin/WD-like repeat-protein; TAIR: AT1G10580.1 Transducin/WD40 repeat-like superfamily protein; Swiss-Prot: sp|O60508|PRP17_HUMAN Pre-mRNA-processing factor 17; TrEMBL-Plants: tr|A0A072V0M7|A0A072V0M7_MEDTR Pre-mRNA splicing factor; Found in the gene: LotjaGi5g1v0161000 | 2 | ||
| – | Transducin/WD-like repeat-protein; TAIR: AT1G10580.1 Transducin/WD40 repeat-like superfamily protein; Swiss-Prot: sp|O60508|PRP17_HUMAN Pre-mRNA-processing factor 17; TrEMBL-Plants: tr|A0A072V0M7|A0A072V0M7_MEDTR Pre-mRNA splicing factor; Found in the gene: LotjaGi5g1v0161000 | 2 |
Co-occuring GO terms 1
A list of co-occurring GO terms within the L. japonicus gene space:
| GO term | Namespace | Name | Observations | Saturation (%) |
|---|---|---|---|---|
| Cellular component | Catalytic step 2 spliceosome | 1 | 33.33 |