Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message
Field | Value |
---|---|
Namespace | Cellular component |
Short description | Spliceosomal complex |
Full defintion | Any of a series of ribonucleoprotein complexes that contain snRNA(s) and small nuclear ribonucleoproteins (snRNPs), and are formed sequentially during the spliceosomal splicing of one or more substrate RNAs, and which also contain the RNA substrate(s) from the initial target RNAs of splicing, the splicing intermediate RNA(s), to the final RNA products. During cis-splicing, the initial target RNA is a single, contiguous RNA transcript, whether mRNA, snoRNA, etc., and the released products are a spliced RNA and an excised intron, generally as a lariat structure. During trans-splicing, there are two initial substrate RNAs, the spliced leader RNA and a pre-mRNA. |
Subterm of |
The relationship of GO:0005681 with other GO terms.
Relationship type | GO terms |
---|---|
Is a | |
Regulates | n.a. |
Part of | n.a. |
Positively regulates | n.a. |
Negatively regulates | n.a. |
A force layout showing the ancestor tree for GO:0005681, and its immediate children. If you wish to explore the tree dynamically, please use the GO Explorer.
This table contains additional metadata associated with the GO entry's definition field.
Field | Value |
---|---|
GOC | mah |
ISBN | |
PMID | The spliceosome: design principles of a dynamic RNP machine. Cell. 2009 Feb 20; 136 (4): 701–18.PMID: 19239890 Ribonucleoproteins (RNPs) mediate key cellular functions such as gene expression and its regulation. Whereas most RNP enzymes are stable in composition and harbor preformed active sites, the spliceosome, which removes noncoding introns from precursor messenger RNAs (pre-mRNAs), follows fundamentally different strategies. In order to provide both accuracy to the recognition of reactive splice sites in the pre-mRNA and flexibility to the choice of splice sites during alternative splicing, the spliceosome exhibits exceptional compositional and structural dynamics that are exploited during substrate-dependent complex assembly, catalytic activation, and active site remodeling. |
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
Transcript | Name | Description | GO terms | GO count |
---|---|---|---|---|
– | PREDICTED: intron-binding protein aquarius-like [Glycine max] gi|356574068|ref|XP_003555174.1| | 2 | ||
– | Unknown protein [Arabidopsis thaliana] gi|15451186|gb|AAK96864.1| | 2 | ||
– | PREDICTED: LOW QUALITY PROTEIN: protein snwA-like [Glycine max] gi|356558906|ref|XP_003547743.1| | 2 | ||
– | CWC15-like protein [Medicago truncatula] gi|357476859|ref|XP_003608715.1| | 2 | ||
– | PREDICTED: splicing factor 3A subunit 3-like [Cicer arietinum] gi|502136296|ref|XP_004502635.1| | 3 | ||
– | PREDICTED: splicing factor 3A subunit 3-like [Fragaria vesca subsp]. vesca] gi|470142668|ref|XP_004307025.1| | 3 | ||
– | Pre-mRNA-processing-splicing factor [Medicago truncatula] gi|357455267|ref|XP_003597914.1| | 2 | ||
– | Pre-mRNA-processing-splicing factor [Medicago truncatula] gi|357455267|ref|XP_003597914.1| | 2 | ||
– | PREDICTED: pre-mRNA-processing-splicing factor 8-like [Cicer arietinum] gi|502080722|ref|XP_004486659.1| | 2 | ||
– | PREDICTED: SNW domain-containing protein 1-like [Cucumis sativus] gi|449443171|ref|XP_004139354.1| | 2 | ||
– | SNW domain-containing protein [Medicago truncatula] gi|357448543|ref|XP_003594547.1| | 2 | ||
– | SNW domain-containing protein [Medicago truncatula] gi|357448543|ref|XP_003594547.1| | 2 | ||
– | PREDICTED: small nuclear ribonucleoprotein E-like [Glycine max] gi|356508935|ref|XP_003523208.1| | 2 | ||
– | PREDICTED: protein CWC15 homolog [Glycine max] gi|356563326|ref|XP_003549915.1| | 2 | ||
– | PREDICTED: protein CWC15 homolog [Glycine max] gi|356563326|ref|XP_003549915.1| | 2 | ||
– | PREDICTED: gem-associated protein 2-like [Glycine max] gi|356536560|ref|XP_003536805.1| | 3 | ||
– | PREDICTED: gem-associated protein 2-like [Cicer arietinum] gi|502121888|ref|XP_004497479.1| | 3 | ||
– | PREDICTED: pre-mRNA-splicing factor 18-like [Glycine max] gi|356504933|ref|XP_003521247.1| | 2 | ||
– | PREDICTED: small nuclear ribonucleoprotein E-like [Glycine max] gi|356508935|ref|XP_003523208.1| | 2 | ||
– | PREDICTED: gem-associated protein 2-like [Cicer arietinum] gi|502121888|ref|XP_004497479.1| | 3 | ||
– | Protein CWC15 like; TAIR: AT3G13200.1 Cwf15 / Cwc15 cell cycle control family protein; Swiss-Prot: sp|Q6NUB2|CW15A_XENLA Protein CWC15 homolog A; TrEMBL-Plants: tr|I3SEE4|I3SEE4_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0275500 | 2 | ||
– | Protein CWC15 like; TAIR: AT3G13200.1 Cwf15 / Cwc15 cell cycle control family protein; Swiss-Prot: sp|Q6NUB2|CW15A_XENLA Protein CWC15 homolog A; TrEMBL-Plants: tr|I3SEE4|I3SEE4_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0275500 | 2 | ||
– | Splicing factor 3A subunit 3; TAIR: AT5G06160.1 splicing factor-like protein; Swiss-Prot: sp|Q9FG01|ATO_ARATH Splicing factor SF3a60 homolog; TrEMBL-Plants: tr|A0A151TS58|A0A151TS58_CAJCA Splicing factor 3A subunit 3; Found in the gene: LotjaGi1g1v0283800 | 3 | ||
– | Pre-mRNA-splicing factor 18; TAIR: AT1G54590.1 pre-mRNA-splicing factor-like protein; Swiss-Prot: sp|Q2HJ41|PRP18_BOVIN Pre-mRNA-splicing factor 18; TrEMBL-Plants: tr|I1N9I5|I1N9I5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0497500_LC | 2 | ||
– | Zinc finger matrin-type 2; TAIR: AT3G05760.1 C2H2 and C2HC zinc fingers superfamily protein; Swiss-Prot: sp|Q96NC0|ZMAT2_HUMAN Zinc finger matrin-type protein 2; TrEMBL-Plants: tr|I3SLF9|I3SLF9_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0747900 | 2 | ||
– | Arginine/serine-rich splicing factor, putative; TAIR: AT3G61860.1 RNA-binding (RRM/RBD/RNP motifs) family protein; Swiss-Prot: sp|P92964|SRS31_ARATH Serine/arginine-rich splicing factor RS31; TrEMBL-Plants: tr|A0A151TY13|A0A151TY13_CAJCA Arginine/serine-rich-splicing factor RSP31; Found in the gene: LotjaGi1g1v0794800 | 2 | ||
– | Arginine/serine-rich splicing factor, putative; TAIR: AT3G61860.1 RNA-binding (RRM/RBD/RNP motifs) family protein; Swiss-Prot: sp|P92964|SRS31_ARATH Serine/arginine-rich splicing factor RS31; TrEMBL-Plants: tr|A0A151TY13|A0A151TY13_CAJCA Arginine/serine-rich-splicing factor RSP31; Found in the gene: LotjaGi1g1v0794800 | 2 | ||
– | Embryo defective 2765; TAIR: AT2G38770.1 P-loop containing nucleoside triphosphate hydrolases superfamily protein; Swiss-Prot: sp|O60306|AQR_HUMAN Intron-binding protein aquarius; TrEMBL-Plants: tr|I1NCV6|I1NCV6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0024500 | 2 | ||
– | Embryo defective 2765; TAIR: AT2G38770.1 P-loop containing nucleoside triphosphate hydrolases superfamily protein; Swiss-Prot: sp|O60306|AQR_HUMAN Intron-binding protein aquarius; TrEMBL-Plants: tr|I1NCV6|I1NCV6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0024500 | 2 | ||
– | Pre-mRNA-processing-splicing factor 8; TAIR: AT1G80070.1 Pre-mRNA-processing-splicing factor; Swiss-Prot: sp|Q9SSD2|PRP8A_ARATH Pre-mRNA-processing-splicing factor 8A; TrEMBL-Plants: tr|V7BXW4|V7BXW4_PHAVU Uncharacterized protein; Found in the gene: LotjaGi3g1v0008200 | 2 | ||
– | Pre-mRNA-processing-splicing factor 8; TAIR: AT1G80070.1 Pre-mRNA-processing-splicing factor; Swiss-Prot: sp|Q9SSD2|PRP8A_ARATH Pre-mRNA-processing-splicing factor 8A; TrEMBL-Plants: tr|V7BXW4|V7BXW4_PHAVU Uncharacterized protein; Found in the gene: LotjaGi3g1v0008200 | 2 | ||
– | Pre-mRNA-processing-splicing factor 8; TAIR: AT1G80070.1 Pre-mRNA-processing-splicing factor; Swiss-Prot: sp|Q9SSD2|PRP8A_ARATH Pre-mRNA-processing-splicing factor 8A; TrEMBL-Plants: tr|V7BXW4|V7BXW4_PHAVU Uncharacterized protein; Found in the gene: LotjaGi3g1v0008200 | 2 | ||
– | Pre-mRNA-processing-splicing factor 8; TAIR: AT1G80070.1 Pre-mRNA-processing-splicing factor; Swiss-Prot: sp|Q9SSD2|PRP8A_ARATH Pre-mRNA-processing-splicing factor 8A; TrEMBL-Plants: tr|V7BXW4|V7BXW4_PHAVU Uncharacterized protein; Found in the gene: LotjaGi3g1v0008200 | 2 | ||
– | Pre-mRNA-processing-splicing factor 8; TAIR: AT1G80070.1 Pre-mRNA-processing-splicing factor; Swiss-Prot: sp|Q9SSD2|PRP8A_ARATH Pre-mRNA-processing-splicing factor 8A; TrEMBL-Plants: tr|A0A151SPN6|A0A151SPN6_CAJCA Pre-mRNA-processing-splicing factor 8; Found in the gene: LotjaGi3g1v0008200 | 2 | ||
– | Arginine/serine-rich splicing factor, putative; TAIR: AT3G61860.1 RNA-binding (RRM/RBD/RNP motifs) family protein; Swiss-Prot: sp|P92964|SRS31_ARATH Serine/arginine-rich splicing factor RS31; TrEMBL-Plants: tr|I1KHT0|I1KHT0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0399000 | 2 | ||
– | Arginine/serine-rich splicing factor, putative; TAIR: AT3G61860.1 RNA-binding (RRM/RBD/RNP motifs) family protein; Swiss-Prot: sp|P92964|SRS31_ARATH Serine/arginine-rich splicing factor RS31; TrEMBL-Plants: tr|I1KHT0|I1KHT0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0399000 | 2 | ||
– | Arginine/serine-rich splicing factor, putative; TAIR: AT3G61860.1 RNA-binding (RRM/RBD/RNP motifs) family protein; Swiss-Prot: sp|P92964|SRS31_ARATH Serine/arginine-rich splicing factor RS31; TrEMBL-Plants: tr|I1KHT1|I1KHT1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0399000 | 2 | ||
– | Arginine/serine-rich splicing factor, putative; TAIR: AT3G61860.1 RNA-binding (RRM/RBD/RNP motifs) family protein; Swiss-Prot: sp|P92964|SRS31_ARATH Serine/arginine-rich splicing factor RS31; TrEMBL-Plants: tr|G7LAU9|G7LAU9_MEDTR RNA-binding (RRM/RBD/RNP motif) family protein; Found in the gene: LotjaGi3g1v0399000 | 2 | ||
– | Arginine/serine-rich splicing factor, putative; TAIR: AT3G61860.1 RNA-binding (RRM/RBD/RNP motifs) family protein; Swiss-Prot: sp|P92964|SRS31_ARATH Serine/arginine-rich splicing factor RS31; TrEMBL-Plants: tr|G7LAU9|G7LAU9_MEDTR RNA-binding (RRM/RBD/RNP motif) family protein; Found in the gene: LotjaGi3g1v0399000 | 2 | ||
– | Arginine/serine-rich splicing factor, putative; TAIR: AT3G61860.1 RNA-binding (RRM/RBD/RNP motifs) family protein; Swiss-Prot: sp|P92964|SRS31_ARATH Serine/arginine-rich splicing factor RS31; TrEMBL-Plants: tr|I1KHT0|I1KHT0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0399000 | 2 | ||
– | Arginine/serine-rich splicing factor, putative; TAIR: AT3G61860.1 RNA-binding (RRM/RBD/RNP motifs) family protein; Swiss-Prot: sp|P92964|SRS31_ARATH Serine/arginine-rich splicing factor RS31; TrEMBL-Plants: tr|A0A151SIS4|A0A151SIS4_CAJCA Arginine/serine-rich-splicing factor RSP31; Found in the gene: LotjaGi3g1v0399000 | 2 | ||
– | Small nuclear ribonucleoprotein Sm D3; TAIR: AT1G20580.1 Small nuclear ribonucleoprotein family protein; Swiss-Prot: sp|Q9LM92|SMD3B_ARATH Small nuclear ribonucleoprotein SmD3b; TrEMBL-Plants: tr|I3SGN2|I3SGN2_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0474900 | 2 | ||
– | SNW domain-containing 1; TAIR: AT1G77180.1 chromatin protein family; Swiss-Prot: sp|O80653|SKIP_ARATH SNW/SKI-interacting protein; TrEMBL-Plants: tr|A0A1J7HB65|A0A1J7HB65_LUPAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0529900 | 2 | ||
– | SNW domain-containing 1; TAIR: AT1G77180.1 chromatin protein family; Swiss-Prot: sp|O80653|SKIP_ARATH SNW/SKI-interacting protein; TrEMBL-Plants: tr|A0A1J7HB65|A0A1J7HB65_LUPAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0529900 | 2 | ||
– | SNW domain-containing 1; TAIR: AT1G77180.1 chromatin protein family; Swiss-Prot: sp|O80653|SKIP_ARATH SNW/SKI-interacting protein; TrEMBL-Plants: tr|A0A1J7HB65|A0A1J7HB65_LUPAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0529900 | 2 | ||
– | SNW domain-containing 1; TAIR: AT1G77180.1 chromatin protein family; Swiss-Prot: sp|O80653|SKIP_ARATH SNW/SKI-interacting protein; TrEMBL-Plants: tr|A0A1J7HB65|A0A1J7HB65_LUPAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0549500 | 2 | ||
– | SNW domain-containing 1; TAIR: AT1G77180.1 chromatin protein family; Swiss-Prot: sp|O80653|SKIP_ARATH SNW/SKI-interacting protein; TrEMBL-Plants: tr|A0A1J7HB65|A0A1J7HB65_LUPAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0549500 | 2 | ||
– | SNW domain-containing 1; TAIR: AT1G77180.1 chromatin protein family; Swiss-Prot: sp|O80653|SKIP_ARATH SNW/SKI-interacting protein; TrEMBL-Plants: tr|A0A1J7HB65|A0A1J7HB65_LUPAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0549500 | 2 | ||
– | SNW domain-containing 1; TAIR: AT1G77180.1 chromatin protein family; Swiss-Prot: sp|O80653|SKIP_ARATH SNW/SKI-interacting protein; TrEMBL-Plants: tr|A0A1J7HB65|A0A1J7HB65_LUPAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0549500 | 2 | ||
– | Protein CWC15 like; TAIR: AT3G13200.1 Cwf15 / Cwc15 cell cycle control family protein; Swiss-Prot: sp|Q6NUB2|CW15A_XENLA Protein CWC15 homolog A; TrEMBL-Plants: tr|I3SEE4|I3SEE4_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0203400 | 2 | ||
– | Zinc finger protein 830; TAIR: AT3G02860.2 zinc ion binding protein; Swiss-Prot: sp|Q63ZM9|ZN830_XENLA Zinc finger protein 830; TrEMBL-Plants: tr|I3SVA5|I3SVA5_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0294700 | 3 | ||
– | Small nuclear ribonucleoprotein; TAIR: AT4G30220.1 small nuclear ribonucleoprotein F; Swiss-Prot: sp|Q9SUM2|RUXF_ARATH Probable small nuclear ribonucleoprotein F; TrEMBL-Plants: tr|I3SY08|I3SY08_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0301200 | 2 | ||
– | Pre-mRNA-splicing factor 18; TAIR: AT1G03140.1 splicing factor Prp18 family protein; Swiss-Prot: sp|Q99633|PRP18_HUMAN Pre-mRNA-splicing factor 18; TrEMBL-Plants: tr|I1JNV3|I1JNV3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0393300 | 2 | ||
– | Pre-mRNA-splicing factor 18; TAIR: AT1G03140.1 splicing factor Prp18 family protein; Swiss-Prot: sp|Q8BM39|PRP18_MOUSE Pre-mRNA-splicing factor 18; TrEMBL-Plants: tr|I1JNV3|I1JNV3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0393500 | 2 | ||
– | Small nuclear ribonucleoprotein Sm D3; TAIR: AT1G20580.1 Small nuclear ribonucleoprotein family protein; Swiss-Prot: sp|Q9LM92|SMD3B_ARATH Small nuclear ribonucleoprotein SmD3b; TrEMBL-Plants: tr|I3T1G1|I3T1G1_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0405100 | 2 | ||
– | Small nuclear ribonucleoprotein; TAIR: AT4G30220.1 small nuclear ribonucleoprotein F; Swiss-Prot: sp|Q9SUM2|RUXF_ARATH Probable small nuclear ribonucleoprotein F; TrEMBL-Plants: tr|I3SY08|I3SY08_LOTJA Uncharacterized protein; Found in the gene: LotjaGi5g1v0029600 | 2 |
A list of co-occurring GO terms within the L. japonicus gene space:
GO term | Namespace | Name | Observations | Saturation (%) |
---|---|---|---|---|
Cellular component | Spliceosomal complex | 1 | 1.79 |