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GO:0090522

Overview

Field Value
Namespace Biological process
Short description Vesicle tethering involved in exocytosis
Full defintion The initial, indirect interaction between a secretory vesicle membrane and a site of exocytosis in the plasma membrane. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior to docking and fusion.
Subterm of

Relationships

The relationship of GO:0090522 with other GO terms.

Relationship type GO terms
Is a
Regulates n.a.
Part of n.a.
Positively regulates n.a.
Negatively regulates n.a.

Ancestor tree

A force layout showing the ancestor tree for GO:0090522, and its immediate children. If you wish to explore the tree dynamically, please use the GO Explorer.

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Additional data

This table contains additional metadata associated with the GO entry's definition field.

Field Value
GOCrn
PMID
Coat/Tether Interactions-Exception or Rule?
Front Cell Dev Biol. ; 4 (): 44.PMID: 27243008

Coat complexes are important for cargo selection and vesicle formation. Recent evidence suggests that they may also be involved in vesicle targeting. Tethering factors, which form an initial bridge between vesicles and the target membrane, may bind to coat complexes. In this review, we ask whether these coat/tether interactions share some common mechanisms, or whether they are special adaptations to the needs of very specific transport steps. We compare recent findings in two multisubunit tethering complexes, the Dsl1 complex and the HOPS complex, and put them into context with the TRAPP I complex as a prominent example for coat/tether interactions. We explore where coat/tether interactions are found, compare their function and structure, and comment on a possible evolution from a common ancestor of coats and tethers.

Associated Lotus transcripts 5

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

Transcript Name Description GO terms GO count
Exocyst complex component Sec8 family protein; TAIR: AT3G10380.1 subunit of exocyst complex 8; Swiss-Prot: sp|Q93YU5|SEC8_ARATH Exocyst complex component SEC8; TrEMBL-Plants: tr|I1LCX3|I1LCX3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0270700 2
Exocyst complex component Sec8 family protein; TAIR: AT3G10380.1 subunit of exocyst complex 8; Swiss-Prot: sp|Q93YU5|SEC8_ARATH Exocyst complex component SEC8; TrEMBL-Plants: tr|I1LCX3|I1LCX3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0270700 2
Exocyst complex component Sec8 family protein; TAIR: AT3G10380.1 subunit of exocyst complex 8; Swiss-Prot: sp|Q93YU5|SEC8_ARATH Exocyst complex component SEC8; TrEMBL-Plants: tr|I1LCX3|I1LCX3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0270700 2
Exocyst complex component Sec8 family protein; TAIR: AT3G10380.1 subunit of exocyst complex 8; Swiss-Prot: sp|Q93YU5|SEC8_ARATH Exocyst complex component SEC8; TrEMBL-Plants: tr|I1LCX3|I1LCX3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0270700 2
Exocyst complex component sec8; TAIR: AT3G10380.1 subunit of exocyst complex 8; Swiss-Prot: sp|Q93YU5|SEC8_ARATH Exocyst complex component SEC8; TrEMBL-Plants: tr|I1LCX3|I1LCX3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0346600_LC 2

Co-occuring GO terms 1

A list of co-occurring GO terms within the L. japonicus gene space:

GO term Namespace Name Observations Saturation (%)
Biological process Vesicle tethering involved in exocytosis 1 20.00