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IPR000701

Source: InterPro

Description

IPR000701 is a Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit.

<p>Succinate dehydrogenase (SDH) is a membrane-bound complex of two main components: a membrane-extrinsic component composed of an FAD-binding flavoprotein and an iron-sulphur protein, and a hydrophobic component composed of a cytochrome b and a membrane anchor protein. The cytochrome b component is a mono-haem transmembrane protein [[cite:PUB00002750], [cite:PUB00003763], [cite:PUB00003349], [cite:PUB00152800]] belonging to a family that includes:</p> <ul><li>Cytochrome b-556 from bacterial SDH (gene sdhC).</li> <li>Cytochrome b560 from the mammalian mitochondrial SDH complex, which is encoded in the mitochondrial genome of some algae and in the plant Marchantia polymorpha.</li> <li>Cytochrome b from yeast mitochondrial SDH complex (gene SDH3 or CYB3).</li> <li>Protein cyt-1 from Caenorhabditis elegans.</li></ul> <p>These cytochromes are proteins of about 130 residues that comprise three transmembrane regions. There are two conserved histidines which may be involved in binding the haem group.</p> <p>This family also includes the subunit C (the cytochrome B subunit) of type B fumarate reductases [[cite:PUB00015792], [cite:PUB00152800]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0016627
Molecular function Oxidoreductase activity, acting on the CH-CH group of donors Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
Subterm of

Associated Lotus transcripts 2

Transcript Name Description Predicted domains Domain count
Lj3g3v2905120.1
– Succinate dehydrogenase subunit [Medicago truncatula] gi|357471271|ref|XP_003605920.1|
Domains
13
LotjaGi3g1v0466200.1
– Succinate dehydrogenase subunit 3; TAIR: AT4G32210.1 succinate dehydrogenase 3-2; Swiss-Prot: sp|P0DKI0|SDH31_ARATH Succinate dehydrogenase subunit 3-1, mitochondrial; TrEMBL-Plants: tr|I3SJ95|I3SJ95_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0466200
Domains
14

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 50.00