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IPR000868

Source: InterPro

Description

IPR000868 is a Isochorismatase-like.

<p>This entry represents a domain found in hydrolase enzymes that belong to the isochorismatase family, including Ureidoacrylate amidohydrolase RutB from Escherichia coli and Nicotinamidase from Saccharomyces cerevisiae. Isochorismatase (also known as 2,3 dihydro-2,3 dihydroxybenzoate synthase) catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydroxybenzoate and pyruvate [[cite:PUB00014434]]. This domain shows a typical helix-sheet-helix sandwich structural architecture, with a central β-sheet made of six parallel strands, three α-helices on one side and two α-helices on the other [[cite:PUB00100812]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0003824
Molecular function Catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
Subterm of

Associated Lotus transcripts 19

Transcript Name Description Predicted domains Domain count
Lj0g3v0218549.1
– Nicotinamidase 1 isoform 2 [Theobroma cacao] gi|508700040|gb|EOX91936.1|
Domains
7
Lj0g3v0258159.1
– PREDICTED: isochorismatase-like isoform X1 [Cicer arietinum] gi|502165060|ref|XP_004513396.1|
Domains
7
Lj0g3v0258169.1
–
Domains
7
Lj4g3v0385900.1
– Nicotinamidase 1 isoform 1 [Theobroma cacao] gi|508706760|gb|EOX98656.1|
Domains
7
Lj5g3v1548750.1
– PREDICTED: peroxyureidoacrylate/ureidoacrylate amidohydrolase RutB-like [Cicer arietinum] gi|502147728|ref|XP_004506892.1|
Domains
6
Lj5g3v1548830.1
– PREDICTED: peroxyureidoacrylate/ureidoacrylate amidohydrolase RutB-like [Cicer arietinum] gi|502147728|ref|XP_004506892.1|
Domains
5
LotjaGi2g1v0021600.1
– Peroxyureidoacrylate/ureidoacrylate amidohydrolase RutB; TAIR: AT5G23230.1 nicotinamidase 2; Swiss-Prot: sp|Q9FMX7|NIC2_ARATH Nicotinamidase 2; TrEMBL-Plants: tr|G7IBE1|G7IBE1_MEDTR Isochorismatase hydrolase family protein; Found in the gene: LotjaGi2g1v0021600
Domains
8
LotjaGi4g1v0039800.1
– Nicotinamidase 1; TAIR: AT2G22570.1 nicotinamidase 1; Swiss-Prot: sp|Q8S8F9|NIC1_ARATH Nicotinamidase 1; TrEMBL-Plants: tr|I3SPQ5|I3SPQ5_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0039800
Domains
8
LotjaGi4g1v0039800.2
– Nicotinamidase 1; TAIR: AT2G22570.1 nicotinamidase 1; Swiss-Prot: sp|Q8S8F9|NIC1_ARATH Nicotinamidase 1; TrEMBL-Plants: tr|I3SPQ5|I3SPQ5_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0039800
Domains
8
LotjaGi4g1v0161200.1
– Nicotinamidase 1; TAIR: AT2G22570.1 nicotinamidase 1; Swiss-Prot: sp|Q8S8F9|NIC1_ARATH Nicotinamidase 1; TrEMBL-Plants: tr|I3T449|I3T449_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0161200
Domains
8
LotjaGi5g1v0239800.1
– Peroxyureidoacrylate/ureidoacrylate amidohydrolase RutB; TAIR: AT3G16190.1 Isochorismatase family protein; Swiss-Prot: sp|Q93Z51|NIC4_ARATH Probable inactive nicotinamidase At3g16190; TrEMBL-Plants: tr|I1KGM1|I1KGM1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0239800
Domains
8
LotjaGi5g1v0239800.2
– Peroxyureidoacrylate/ureidoacrylate amidohydrolase RutB; TAIR: AT3G16190.1 Isochorismatase family protein; Swiss-Prot: sp|Q93Z51|NIC4_ARATH Probable inactive nicotinamidase At3g16190; TrEMBL-Plants: tr|I1KGM1|I1KGM1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0239800
Domains
8
LotjaGi5g1v0239800.3
– Peroxyureidoacrylate/ureidoacrylate amidohydrolase RutB; TAIR: AT3G16190.1 Isochorismatase family protein; Swiss-Prot: sp|Q93Z51|NIC4_ARATH Probable inactive nicotinamidase At3g16190; TrEMBL-Plants: tr|I1KGM1|I1KGM1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0239800
Domains
8
LotjaGi5g1v0239800.4
– Peroxyureidoacrylate/ureidoacrylate amidohydrolase RutB; TAIR: AT3G16190.1 Isochorismatase family protein; Swiss-Prot: sp|Q93Z51|NIC4_ARATH Probable inactive nicotinamidase At3g16190; TrEMBL-Plants: tr|I1KGM1|I1KGM1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0239800
Domains
8
LotjaGi5g1v0239900.1
– Peroxyureidoacrylate/ureidoacrylate amidohydrolase RutB; TAIR: AT3G16190.1 Isochorismatase family protein; Swiss-Prot: sp|Q93Z51|NIC4_ARATH Probable inactive nicotinamidase At3g16190; TrEMBL-Plants: tr|I1KGM1|I1KGM1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0239900
Domains
8
LotjaGi5g1v0239900.2
– Peroxyureidoacrylate/ureidoacrylate amidohydrolase RutB; TAIR: AT3G16190.1 Isochorismatase family protein; Swiss-Prot: sp|Q93Z51|NIC4_ARATH Probable inactive nicotinamidase At3g16190; TrEMBL-Plants: tr|I1KGM1|I1KGM1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0239900
Domains
8
LotjaGi5g1v0240100_LC.1
– Peroxyureidoacrylate/ureidoacrylate amidohydrolase RutB; TAIR: AT3G16190.1 Isochorismatase family protein; Swiss-Prot: sp|Q93Z51|NIC4_ARATH Probable inactive nicotinamidase At3g16190; TrEMBL-Plants: tr|I3SHE0|I3SHE0_LOTJA Uncharacterized protein; Found in the gene: LotjaGi5g1v0240100_LC
Domains
8
LotjaGi5g1v0240100_LC.2
– Peroxyureidoacrylate/ureidoacrylate amidohydrolase RutB; TAIR: AT3G16190.1 Isochorismatase family protein; Swiss-Prot: sp|Q93Z51|NIC4_ARATH Probable inactive nicotinamidase At3g16190; TrEMBL-Plants: tr|I3SHE0|I3SHE0_LOTJA Uncharacterized protein; Found in the gene: LotjaGi5g1v0240100_LC
Domains
8
LotjaGi5g1v0240100_LC.3
– Peroxyureidoacrylate/ureidoacrylate amidohydrolase RutB; TAIR: AT3G16190.1 Isochorismatase family protein; Swiss-Prot: sp|Q93Z51|NIC4_ARATH Probable inactive nicotinamidase At3g16190; TrEMBL-Plants: tr|I3SHE0|I3SHE0_LOTJA Uncharacterized protein; Found in the gene: LotjaGi5g1v0240100_LC
Domains
8

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd00431 CDD 1 5.26