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IPR001597

Description

IPR001597 is a Aromatic amino acid beta-eliminating lyase/threonine aldolase.

<p>This domain is found in many tryptophanases (tryptophan indole-lyase, TNase), tyrosine phenol-lyases (TPL) and threonine aldolases. It is involved in the degradation of amino acids. The glycine cleavage system is composed of four proteins: P, T, L and H. In Bacillus subtilis, the P 'protein' is an heterodimer of two subunits. The glycine cleavage system catalyses the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Biological process Cellular amino acid metabolic process The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.
Molecular function Lyase activity Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.

Associated Lotus transcripts 16

Transcript Name Description Predicted domains Domain count
PREDICTED: L-allo-threonine aldolase-like [Glycine max] gi|356576676|ref|XP_003556456.1| 8
PREDICTED: L-allo-threonine aldolase-like [Glycine max] gi|356576676|ref|XP_003556456.1| 8
PREDICTED: L-allo-threonine aldolase-like [Glycine max] gi|356576676|ref|XP_003556456.1| 8
PREDICTED: L-allo-threonine aldolase-like [Glycine max] gi|356505991|ref|XP_003521772.1| 13
PREDICTED: L-allo-threonine aldolase-like [Glycine max] gi|356576676|ref|XP_003556456.1| 12
L-allo-threonine aldolase [Medicago truncatula] gi|357441389|ref|XP_003590972.1| 13
L-allo-threonine aldolase; TAIR: AT1G08630.1 threonine aldolase 1; Swiss-Prot: sp|Q8RXU4|THA1_ARATH Probable low-specificity L-threonine aldolase 1; TrEMBL-Plants: tr|K7N506|K7N506_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0335400_LC 11
L-allo-threonine aldolase; TAIR: AT1G08630.1 threonine aldolase 1; Swiss-Prot: sp|Q8RXU4|THA1_ARATH Probable low-specificity L-threonine aldolase 1; TrEMBL-Plants: tr|I3STQ7|I3STQ7_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0784900 13
L-allo-threonine aldolase; TAIR: AT1G08630.1 threonine aldolase 1; Swiss-Prot: sp|Q8RXU4|THA1_ARATH Probable low-specificity L-threonine aldolase 1; TrEMBL-Plants: tr|I3STQ7|I3STQ7_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0784900 13
L-allo-threonine aldolase; TAIR: AT1G08630.1 threonine aldolase 1; Swiss-Prot: sp|Q8RXU4|THA1_ARATH Probable low-specificity L-threonine aldolase 1; TrEMBL-Plants: tr|I3STQ7|I3STQ7_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0784900 13
L-allo-threonine aldolase; TAIR: AT1G08630.1 threonine aldolase 1; Swiss-Prot: sp|Q8RXU4|THA1_ARATH Probable low-specificity L-threonine aldolase 1; TrEMBL-Plants: tr|I3STQ7|I3STQ7_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0784900 13
L-allo-threonine aldolase; TAIR: AT1G08630.1 threonine aldolase 1; Swiss-Prot: sp|Q8RXU4|THA1_ARATH Probable low-specificity L-threonine aldolase 1; TrEMBL-Plants: tr|I3STQ7|I3STQ7_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0784900 13
L-allo-threonine aldolase; TAIR: AT1G08630.1 threonine aldolase 1; Swiss-Prot: sp|Q8RXU4|THA1_ARATH Probable low-specificity L-threonine aldolase 1; TrEMBL-Plants: tr|I1NIN3|I1NIN3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0208600 12
L-allo-threonine aldolase; TAIR: AT1G08630.1 threonine aldolase 1; Swiss-Prot: sp|Q8RXU4|THA1_ARATH Probable low-specificity L-threonine aldolase 1; TrEMBL-Plants: tr|I1NIN3|I1NIN3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0208600 12
L-allo-threonine aldolase; TAIR: AT1G08630.1 threonine aldolase 1; Swiss-Prot: sp|Q8RXU4|THA1_ARATH Probable low-specificity L-threonine aldolase 1; TrEMBL-Plants: tr|V7BDV5|V7BDV5_PHAVU Uncharacterized protein; Found in the gene: LotjaGi5g1v0208600 10
L-allo-threonine aldolase; TAIR: AT1G08630.1 threonine aldolase 1; Swiss-Prot: sp|Q8RXU4|THA1_ARATH Probable low-specificity L-threonine aldolase 1; TrEMBL-Plants: tr|V7BDV5|V7BDV5_PHAVU Uncharacterized protein; Found in the gene: LotjaGi5g1v0208600 12

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
SSF53383 SUPERFAMILY 1 6.25