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IPR001663 is a Aromatic-ring-hydroxylating dioxygenase, alpha subunit.
<p>Aromatic ring hydroxylating dioxygenases are multicomponent 1,2-dioxygenase complexes that convert closed-ring structures to non-aromatic cis-diols [[cite:PUB00002151]]. The complex has both hydroxylase and electron transfer components. The hydroxylase component is itself composed of two subunits: an alpha-subunit of about 50kDa, and a beta-subunit of about 20kDa. The electron transfer component is either composed of two subunits: a ferredoxin and a ferredoxin reductase or by a single bifunctional ferredoxin/reductase subunit. Sequence analysis of hydroxylase subunits of ring hydroxylating systems (including toluene, benzene and napthalene 1,2-dioxygenases) suggests they are derived from a common ancestor [[cite:PUB00002151]]. The alpha-subunit binds both a Rieske-like 2Fe-2S cluster and an iron atom: conserved Cys and His residues in the N-terminal region may provide 2Fe-2S ligands, while conserved His and Tyr residues may coordinate the iron. The beta subunit may be responsible for the substrate specificity of the dioxygenase system [[cite:PUB00002151]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Biological process | Cellular metabolic process | The chemical reactions and pathways by which individual cells transform chemical substances. | ||
| Molecular function | 2 iron, 2 sulfur cluster binding | Interacting selectively and non-covalently with a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands. | ||
| Biological process | Oxidation-reduction process | A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: choline monooxygenase, chloroplastic-like [Cicer arietinum] gi|502150350|ref|XP_004507911.1| | 9 | ||
| – | PREDICTED: choline monooxygenase, chloroplastic-like [Glycine max] gi|356562034|ref|XP_003549280.1| | 14 | ||
| – | PREDICTED: choline monooxygenase, chloroplastic-like [Cicer arietinum] gi|502150350|ref|XP_004507911.1| | 11 | ||
| – | Choline monooxygenase; TAIR: AT4G29890.1 choline monooxygenase, putative (CMO-like); Swiss-Prot: sp|Q9SZR0|CHMO_ARATH Choline monooxygenase, chloroplastic; TrEMBL-Plants: tr|I1MSJ9|I1MSJ9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0307100 | 15 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd08883 | CDD | 1 | 25.00 |