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IPR036922 is a Rieske [2Fe-2S] iron-sulphur domain superfamily.
<p>There are multiple types of iron-sulphur clusters which are grouped into three main categories based on their atomic content: [2Fe-2S], [3Fe-4S], [4Fe-4S] (see [prositedoc:PDOC00176]), and other hybrid or mixed metal types. Two general types of [2Fe-2S] clusters are known and they differ in their coordinating residues. The ferredoxin-type [2Fe-2S] clusters are coordinated to the protein by four cysteine residues (see [prositedoc:PDOC00175]). The Rieske-type [2Fe-2S] cluster is coordinated to its protein by two cysteine residues and two histidine residues [[cite:PUB00043836], [cite:PUB00043837]].</p> <p>The structure of several Rieske domains has been solved [[cite:PUB00005280]]. It contains three layers of antiparallel β-sheets forming two β-sandwiches. Both β-sandwiches share the central sheet 2. The metal-binding site is at the top of the β-sandwich formed by the sheets 2 and 3. The Fe1 iron of the Rieske cluster is coordinated by two cysteines while the other iron Fe2 is coordinated by two histidines. Two inorganic sulphide ions bridge the two iron ions forming a flat, rhombic cluster.</p> <p>Rieske-type iron-sulphur clusters are common to electron transfer chains of mitochondria and chloroplast and to non-haem iron oxygenase systems:</p> <ul> <li>The Rieske protein of the Ubiquinol-cytochrome c reductase ([ec:7.1.1.8]) (also known as the bc1 complex or complex III), a complex of the electron transport chains of mitochondria and of some aerobic prokaryotes; it catalyses the oxidoreduction of ubiquinol and cytochrome c.</li> <li>The Rieske protein of chloroplastic plastoquinone-plastocyanin reductase ([ec:1.10.9.1]) (also known as the b6f complex). It is functionally similar to the bc1 complex and catalyses the oxidoreduction of plastoquinol and cytochrome f.</li> <li>Bacterial naphthalene 1,2-dioxygenase subunit alpha, a component of the naphthalene dioxygenase (NDO) multicomponent enzyme system which catalyses the incorporation of both atoms of molecular oxygen into naphthalene to form cis-naphthalene dihydrodiol.</li> <li>Bacterial 3-phenylpropionate dioxygenase ferredoxin subunit.</li> <li>Bacterial toluene monooxygenase.</li> <li>Bacterial biphenyl dioxygenase.</li> </ul>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Oxidoreductase activity | Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. | ||
| Molecular function | 2 iron, 2 sulfur cluster binding | Interacting selectively and non-covalently with a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands. | ||
| Biological process | Oxidation-reduction process | A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Chlorophyllide A oxygenase; TAIR: AT1G44446.1 Pheophorbide a oxygenase family protein with Rieske 2Fe-2S domain-containing protein; Swiss-Prot: sp|Q9MBA1|CAO_ARATH Chlorophyllide a oxygenase, chloroplastic; TrEMBL-Plants: tr|A0A151RSX8|A0A151RSX8_CAJCA Uncharacterized protein; Found in the gene: LotjaGi1g1v0159200 | 16 | ||
| – | Chlorophyllide A oxygenase; TAIR: AT1G44446.1 Pheophorbide a oxygenase family protein with Rieske 2Fe-2S domain-containing protein; Swiss-Prot: sp|Q8S7E1|CAO_ORYSJ Chlorophyllide a oxygenase, chloroplastic; TrEMBL-Plants: tr|A0A151RSX8|A0A151RSX8_CAJCA Uncharacterized protein; Found in the gene: LotjaGi1g1v0159200 | 16 | ||
| – | Pheophorbide a oxygenase, chloroplastic; TAIR: AT2G24820.1 translocon at the inner envelope membrane of chloroplasts 55-II; Swiss-Prot: sp|O49931|TIC55_PEA Protein TIC 55, chloroplastic; TrEMBL-Plants: tr|A0A151RNW1|A0A151RNW1_CAJCA Uncharacterized protein; Found in the gene: LotjaGi1g1v0375800 | 15 | ||
| – | Cytochrome b-c1 complex subunit Rieske, mitochondrial; TAIR: AT5G13430.1 Ubiquinol-cytochrome C reductase iron-sulfur subunit; Swiss-Prot: sp|P49727|UCRI_MAIZE Cytochrome b-c1 complex subunit Rieske, mitochondrial; TrEMBL-Plants: tr|I3SAX8|I3SAX8_LOTJA Cytochrome b-c1 complex subunit Rieske, mitochondrial; Found in the gene: LotjaGi1g1v0633700 | 22 | ||
| – | Cytochrome b-c1 complex subunit Rieske, mitochondrial; TAIR: AT5G13440.1 Ubiquinol-cytochrome C reductase iron-sulfur subunit; Swiss-Prot: sp|P51132|UCRI2_TOBAC Cytochrome b-c1 complex subunit Rieske-2, mitochondrial; TrEMBL-Plants: tr|A0A0L9T7J6|A0A0L9T7J6_PHAAN Cytochrome b-c1 complex subunit Rieske, mitochondrial; Found in the gene: LotjaGi2g1v0104600 | 25 | ||
| – | Photosystem II 22 kDa protein; TAIR: AT1G71500.1 Rieske (2Fe-2S) domain-containing protein; Swiss-Prot: sp|P51355|YCF17_PORPU Uncharacterized protein ycf17; TrEMBL-Plants: tr|A0A151SCU8|A0A151SCU8_CAJCA Uncharacterized protein; Found in the gene: LotjaGi2g1v0444900 | 11 | ||
| – | Cytochrome b6-f complex iron-sulfur subunit; TAIR: AT4G03280.1 photosynthetic electron transfer C; Swiss-Prot: sp|P26291|UCRIA_PEA Cytochrome b6-f complex iron-sulfur subunit, chloroplastic; TrEMBL-Plants: tr|I3RZ73|I3RZ73_LOTJA Cytochrome b6-f complex iron-sulfur subunit; Found in the gene: LotjaGi3g1v0438600 | 20 | ||
| – | Cytochrome b6-f complex iron-sulfur subunit; TAIR: AT4G03280.1 photosynthetic electron transfer C; Swiss-Prot: sp|P26291|UCRIA_PEA Cytochrome b6-f complex iron-sulfur subunit, chloroplastic; TrEMBL-Plants: tr|I3RZ73|I3RZ73_LOTJA Cytochrome b6-f complex iron-sulfur subunit; Found in the gene: LotjaGi3g1v0438600 | 20 | ||
| – | Pheophorbide a oxygenase, chloroplastic; TAIR: AT3G44880.1 Pheophorbide a oxygenase family protein with Rieske 2Fe-2S domain-containing protein; Swiss-Prot: sp|Q9FYC2|PAO_ARATH Pheophorbide a oxygenase, chloroplastic; TrEMBL-Plants: tr|I1LKY8|I1LKY8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0484200 | 21 | ||
| – | Choline monooxygenase; TAIR: AT4G29890.1 choline monooxygenase, putative (CMO-like); Swiss-Prot: sp|Q9SZR0|CHMO_ARATH Choline monooxygenase, chloroplastic; TrEMBL-Plants: tr|I1MSJ9|I1MSJ9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0307100 | 15 | ||
| – | Pheophorbide a oxygenase, chloroplastic; TAIR: AT4G25650.1 ACD1-like protein; Swiss-Prot: sp|Q8W496|PTC52_ARATH Protochlorophyllide-dependent translocon component 52, chloroplastic; TrEMBL-Plants: tr|G7LIM7|G7LIM7_MEDTR Chlorophyllide A oxygenase; Found in the gene: LotjaGi4g1v0375900 | 16 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd03480 | CDD | 1 | 9.09 |