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GO:0051537

View this GO term in other databases

Overview

Field Value
Namespace Molecular function
Short description 2 iron, 2 sulfur cluster binding
Full defintion Interacting selectively and non-covalently with a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands.
Subterm of

Relationships

The relationship of GO:0051537 with other GO terms.

Relationship type GO terms
Is a
Regulates n.a.
Part of n.a.
Positively regulates n.a.
Negatively regulates n.a.

Ancestor tree

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Additional data

This table contains additional metadata associated with the GO entry's definition field.

Field Value
GOCai
WikipediaIron-sulfur_cluster
PMID
Structure, function, and formation of biological iron-sulfur clusters.Johnson DC, Dean DR, Smith AD, Johnson MK
Annu Rev Biochem. 2005; 74 (): 247–81.PMID: 15952888

Iron-sulfur [Fe-S] clusters are ubiquitous and evolutionary ancient prosthetic groups that are required to sustain fundamental life processes. Owing to their remarkable structural plasticity and versatile chemical/electronic features [Fe-S] clusters participate in electron transfer, substrate binding/activation, iron/sulfur storage, regulation of gene expression, and enzyme activity. Formation of intracellular [Fe-S] clusters does not occur spontaneously but requires a complex biosynthetic machinery. Three different types of [Fe-S] cluster biosynthetic systems have been discovered, and all of them are mechanistically unified by the requirement for a cysteine desulfurase and the participation of an [Fe-S] cluster scaffolding protein. Important mechanistic questions related to [Fe-S] cluster biosynthesis involve the molecular details of how [Fe-S] clusters are assembled on scaffold proteins, how [Fe-S] clusters are transferred from scaffolds to target proteins, how various accessory proteins participate in [Fe-S] protein maturation, and how the biosynthetic process is regulated.

Associated Lotus transcripts 56

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

Transcript Name Description GO terms GO count
Lj0g3v0271779.1
– PREDICTED: protein TIC 55, chloroplastic-like [Cicer arietinum] gi|502132507|ref|XP_004501394.1|
GO terms
3
Lj0g3v0323599.1
– PREDICTED: ferredoxin-2-like [Cicer arietinum] gi|502152646|ref|XP_004509024.1|
GO terms
3
Lj0g3v0362219.1
– PREDICTED: chlorophyllide a oxygenase, chloroplastic-like [Cicer arietinum] gi|502124009|ref|XP_004498345.1|
GO terms
4
Lj1g3v3740570.1
– PREDICTED: succinate dehydrogenase [ubiquinone] gi|502089528|ref|XP_004488937.1|
GO terms
1
Lj1g3v3751710.1
– PREDICTED: succinate dehydrogenase [ubiquinone] gi|502089528|ref|XP_004488937.1|
GO terms
1
Lj1g3v3751710.2
– PREDICTED: succinate dehydrogenase [ubiquinone] gi|502089528|ref|XP_004488937.1|
GO terms
1
Lj1g3v3904490.1
– Ubiquinol-cytochrome c reductase iron-sulfur subunit [Medicago truncatula] gi|357508447|ref|XP_003624512.1|
GO terms
3
Lj1g3v4897990.1
– PREDICTED: ferredoxin-3, chloroplastic-like isoform X1 [Cicer arietinum] gi|502120992|ref|XP_004497151.1|
GO terms
3
Lj2g3v0484940.1
– PREDICTED: CDGSH iron-sulfur domain-containing protein 2-like [Glycine max] gi|356559911|ref|XP_003548239.1|
GO terms
2
Lj2g3v2101940.1
– Os11g0242400 [Oryza sativa Japonica Group] gi|115484891|ref|NP_001067589.1|
GO terms
3
Lj3g3v1694660.1
– PREDICTED: xanthine dehydrogenase 1-like isoform X2 [Cicer arietinum] gi|502081768|ref|XP_004486962.1|
GO terms
1
Lj3g3v2742950.1
– PREDICTED: cytochrome b6-f complex iron-sulfur subunit, chloroplastic-like [Glycine max] gi|356549980|ref|XP_003543368.1|
GO terms
5
Lj3g3v2994500.2
– Ferredoxin-6 [Medicago truncatula] gi|357471641|ref|XP_003606105.1|
GO terms
3
Lj3g3v3032090.1
– PREDICTED: pheophorbide a oxygenase, chloroplastic-like [Cicer arietinum] gi|502145563|ref|XP_004506081.1|
GO terms
3
Lj4g3v2139640.1
– PREDICTED: choline monooxygenase, chloroplastic-like [Cicer arietinum] gi|502150350|ref|XP_004507911.1|
GO terms
4
Lj4g3v2139640.2
– PREDICTED: choline monooxygenase, chloroplastic-like [Cicer arietinum] gi|502150350|ref|XP_004507911.1|
GO terms
3
Lj4g3v2139640.3
– PREDICTED: choline monooxygenase, chloroplastic-like [Glycine max] gi|356562034|ref|XP_003549280.1|
GO terms
5
Lj4g3v2139640.4
– PREDICTED: choline monooxygenase, chloroplastic-like [Cicer arietinum] gi|502150350|ref|XP_004507911.1|
GO terms
5
Lj4g3v2215060.1
– PREDICTED: 2Fe-2S ferredoxin-like [Glycine max] gi|356547972|ref|XP_003542378.1|
GO terms
2
Lj4g3v2690750.1
– 2Fe-2S ferredoxin-like superfamily protein, A,ATFD2 [Theobroma cacao] gi|508706205|gb|EOX98101.1|
GO terms
3
Lj4g3v3096070.1
– PREDICTED: 2Fe-2S ferredoxin-like isoform X1 [Cicer arietinum] gi|502080842|ref|XP_004486700.1|
GO terms
2
Lj6g3v2274750.2
– PREDICTED: ferredoxin-1, chloroplastic-like [Cicer arietinum] gi|502076836|ref|XP_004485473.1|
GO terms
3
LotjaGi1g1v0059700.1
– Aldehyde oxidase; TAIR: AT3G43600.1 aldehyde oxidase 2; Swiss-Prot: sp|Q7G192|ALDO2_ARATH Indole-3-acetaldehyde oxidase; TrEMBL-Plants: tr|A0A1J7IPN3|A0A1J7IPN3_LUPAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0059700
GO terms
1
LotjaGi1g1v0059900.1
– Aldehyde oxidase; TAIR: AT3G43600.1 aldehyde oxidase 2; Swiss-Prot: sp|Q7G192|ALDO2_ARATH Indole-3-acetaldehyde oxidase; TrEMBL-Plants: tr|K7KB27|K7KB27_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0059900
GO terms
1
LotjaGi1g1v0059900.2
– Aldehyde oxidase; TAIR: AT3G43600.1 aldehyde oxidase 2; Swiss-Prot: sp|Q7G192|ALDO2_ARATH Indole-3-acetaldehyde oxidase; TrEMBL-Plants: tr|K7KB27|K7KB27_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0059900
GO terms
1
LotjaGi1g1v0060000.1
– Aldehyde oxidase; TAIR: AT2G27150.1 abscisic aldehyde oxidase 3; Swiss-Prot: sp|Q7G9P4|ALDO3_ARATH Abscisic-aldehyde oxidase; TrEMBL-Plants: tr|K7KB27|K7KB27_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0060000
GO terms
1
LotjaGi1g1v0060000.4
– Aldehyde oxidase; TAIR: AT2G27150.1 abscisic aldehyde oxidase 3; Swiss-Prot: sp|Q7G9P4|ALDO3_ARATH Abscisic-aldehyde oxidase; TrEMBL-Plants: tr|K7KB27|K7KB27_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0060000
GO terms
1
LotjaGi1g1v0159200.1
– Chlorophyllide A oxygenase; TAIR: AT1G44446.1 Pheophorbide a oxygenase family protein with Rieske 2Fe-2S domain-containing protein; Swiss-Prot: sp|Q9MBA1|CAO_ARATH Chlorophyllide a oxygenase, chloroplastic; TrEMBL-Plants: tr|A0A151RSX8|A0A151RSX8_CAJCA Uncharacterized protein; Found in the gene: LotjaGi1g1v0159200
GO terms
4
LotjaGi1g1v0159200.2
– Chlorophyllide A oxygenase; TAIR: AT1G44446.1 Pheophorbide a oxygenase family protein with Rieske 2Fe-2S domain-containing protein; Swiss-Prot: sp|Q8S7E1|CAO_ORYSJ Chlorophyllide a oxygenase, chloroplastic; TrEMBL-Plants: tr|A0A151RSX8|A0A151RSX8_CAJCA Uncharacterized protein; Found in the gene: LotjaGi1g1v0159200
GO terms
4
LotjaGi1g1v0375800.1
– Pheophorbide a oxygenase, chloroplastic; TAIR: AT2G24820.1 translocon at the inner envelope membrane of chloroplasts 55-II; Swiss-Prot: sp|O49931|TIC55_PEA Protein TIC 55, chloroplastic; TrEMBL-Plants: tr|A0A151RNW1|A0A151RNW1_CAJCA Uncharacterized protein; Found in the gene: LotjaGi1g1v0375800
GO terms
3
LotjaGi1g1v0616900.1
– Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; TAIR: AT5G40650.1 succinate dehydrogenase 2-2; Swiss-Prot: sp|Q8LB02|SDHB2_ARATH Succinate dehydrogenase [ubiquinone] iron-sulfur subunit 2, mitochondrial; TrEMBL-Plants: tr|A0A0S3SJV1|A0A0S3SJV1_PHAAN Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Found in the gene: LotjaGi1g1v0616900
GO terms
1
LotjaGi1g1v0616900.2
– Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; TAIR: AT5G40650.1 succinate dehydrogenase 2-2; Swiss-Prot: sp|Q8LB02|SDHB2_ARATH Succinate dehydrogenase [ubiquinone] iron-sulfur subunit 2, mitochondrial; TrEMBL-Plants: tr|A0A0S3SJV1|A0A0S3SJV1_PHAAN Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Found in the gene: LotjaGi1g1v0616900
GO terms
1
LotjaGi1g1v0617600.1
– Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; TAIR: AT5G40650.1 succinate dehydrogenase 2-2; Swiss-Prot: sp|Q8LB02|SDHB2_ARATH Succinate dehydrogenase [ubiquinone] iron-sulfur subunit 2, mitochondrial; TrEMBL-Plants: tr|A0A0S3SJV1|A0A0S3SJV1_PHAAN Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Found in the gene: LotjaGi1g1v0617600
GO terms
1
LotjaGi1g1v0617600.2
– Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; TAIR: AT5G40650.1 succinate dehydrogenase 2-2; Swiss-Prot: sp|Q8LB02|SDHB2_ARATH Succinate dehydrogenase [ubiquinone] iron-sulfur subunit 2, mitochondrial; TrEMBL-Plants: tr|A0A0S3SJV1|A0A0S3SJV1_PHAAN Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Found in the gene: LotjaGi1g1v0617600
GO terms
1
LotjaGi1g1v0617600.3
– Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; TAIR: AT5G40650.1 succinate dehydrogenase 2-2; Swiss-Prot: sp|Q8LB02|SDHB2_ARATH Succinate dehydrogenase [ubiquinone] iron-sulfur subunit 2, mitochondrial; TrEMBL-Plants: tr|A0A0S3SJV1|A0A0S3SJV1_PHAAN Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Found in the gene: LotjaGi1g1v0617600
GO terms
1
LotjaGi1g1v0633700.1
– Cytochrome b-c1 complex subunit Rieske, mitochondrial; TAIR: AT5G13430.1 Ubiquinol-cytochrome C reductase iron-sulfur subunit; Swiss-Prot: sp|P49727|UCRI_MAIZE Cytochrome b-c1 complex subunit Rieske, mitochondrial; TrEMBL-Plants: tr|I3SAX8|I3SAX8_LOTJA Cytochrome b-c1 complex subunit Rieske, mitochondrial; Found in the gene: LotjaGi1g1v0633700
GO terms
3
LotjaGi1g1v0765600.1
– Ferredoxin family protein; TAIR: AT2G27510.1 ferredoxin 3; Swiss-Prot: sp|P27788|FER3_MAIZE Ferredoxin-3, chloroplastic; TrEMBL-Plants: tr|I3S8M2|I3S8M2_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0765600
GO terms
3
LotjaGi1g1v0765600.2
– Ferredoxin family protein; TAIR: AT2G27510.1 ferredoxin 3; Swiss-Prot: sp|P27788|FER3_MAIZE Ferredoxin-3, chloroplastic; TrEMBL-Plants: tr|I3S8M2|I3S8M2_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0765600
GO terms
3
LotjaGi2g1v0104600.1
– Cytochrome b-c1 complex subunit Rieske, mitochondrial; TAIR: AT5G13440.1 Ubiquinol-cytochrome C reductase iron-sulfur subunit; Swiss-Prot: sp|P51132|UCRI2_TOBAC Cytochrome b-c1 complex subunit Rieske-2, mitochondrial; TrEMBL-Plants: tr|A0A0L9T7J6|A0A0L9T7J6_PHAAN Cytochrome b-c1 complex subunit Rieske, mitochondrial; Found in the gene: LotjaGi2g1v0104600
GO terms
3
LotjaGi2g1v0158700.1
– CDGSH iron-sulfur domain-containing protein 2; TAIR: AT5G51720.1 2 iron, 2 sulfur cluster binding protein; Swiss-Prot: sp|Q9FLI7|NEET_ARATH CDGSH iron-sulfur domain-containing protein NEET; TrEMBL-Plants: tr|I3T106|I3T106_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0158700
GO terms
2
LotjaGi2g1v0158700.2
– CDGSH iron-sulfur domain-containing protein 2; TAIR: AT5G51720.1 2 iron, 2 sulfur cluster binding protein; Swiss-Prot: sp|Q9FLI7|NEET_ARATH CDGSH iron-sulfur domain-containing protein NEET; TrEMBL-Plants: tr|I3T106|I3T106_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0158700
GO terms
2
LotjaGi2g1v0444900.1
– Photosystem II 22 kDa protein; TAIR: AT1G71500.1 Rieske (2Fe-2S) domain-containing protein; Swiss-Prot: sp|P51355|YCF17_PORPU Uncharacterized protein ycf17; TrEMBL-Plants: tr|A0A151SCU8|A0A151SCU8_CAJCA Uncharacterized protein; Found in the gene: LotjaGi2g1v0444900
GO terms
3
LotjaGi3g1v0288100.1
– Xanthine dehydrogenase; TAIR: AT4G34890.1 xanthine dehydrogenase 1; Swiss-Prot: sp|Q8GUQ8|XDH1_ARATH Xanthine dehydrogenase 1; TrEMBL-Plants: tr|A0A0B2RE38|A0A0B2RE38_GLYSO Xanthine dehydrogenase; Found in the gene: LotjaGi3g1v0288100
GO terms
1
LotjaGi3g1v0288100.4
– Xanthine dehydrogenase; TAIR: AT4G34890.1 xanthine dehydrogenase 1; Swiss-Prot: sp|Q8GUQ8|XDH1_ARATH Xanthine dehydrogenase 1; TrEMBL-Plants: tr|A0A0R0G5H5|A0A0R0G5H5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0288100
GO terms
1
LotjaGi3g1v0288100.5
– Xanthine dehydrogenase/oxidase; TAIR: AT4G34890.1 xanthine dehydrogenase 1; Swiss-Prot: sp|Q8GUQ8|XDH1_ARATH Xanthine dehydrogenase 1; TrEMBL-Plants: tr|A0A0B2RM17|A0A0B2RM17_GLYSO Xanthine dehydrogenase; Found in the gene: LotjaGi3g1v0288100
GO terms
1
LotjaGi3g1v0438600.1
– Cytochrome b6-f complex iron-sulfur subunit; TAIR: AT4G03280.1 photosynthetic electron transfer C; Swiss-Prot: sp|P26291|UCRIA_PEA Cytochrome b6-f complex iron-sulfur subunit, chloroplastic; TrEMBL-Plants: tr|I3RZ73|I3RZ73_LOTJA Cytochrome b6-f complex iron-sulfur subunit; Found in the gene: LotjaGi3g1v0438600
GO terms
3
LotjaGi3g1v0438600.2
– Cytochrome b6-f complex iron-sulfur subunit; TAIR: AT4G03280.1 photosynthetic electron transfer C; Swiss-Prot: sp|P26291|UCRIA_PEA Cytochrome b6-f complex iron-sulfur subunit, chloroplastic; TrEMBL-Plants: tr|I3RZ73|I3RZ73_LOTJA Cytochrome b6-f complex iron-sulfur subunit; Found in the gene: LotjaGi3g1v0438600
GO terms
3
LotjaGi3g1v0477000.1
– Ferredoxin family protein; TAIR: AT2G27510.1 ferredoxin 3; Swiss-Prot: sp|P27788|FER3_MAIZE Ferredoxin-3, chloroplastic; TrEMBL-Plants: tr|I3S8K1|I3S8K1_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0477000
GO terms
3
LotjaGi3g1v0477000.2
– Ferredoxin family protein; TAIR: AT2G27510.1 ferredoxin 3; Swiss-Prot: sp|P27788|FER3_MAIZE Ferredoxin-3, chloroplastic; TrEMBL-Plants: tr|I3S8K1|I3S8K1_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0477000
GO terms
3
LotjaGi3g1v0484200.1
– Pheophorbide a oxygenase, chloroplastic; TAIR: AT3G44880.1 Pheophorbide a oxygenase family protein with Rieske 2Fe-2S domain-containing protein; Swiss-Prot: sp|Q9FYC2|PAO_ARATH Pheophorbide a oxygenase, chloroplastic; TrEMBL-Plants: tr|I1LKY8|I1LKY8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0484200
GO terms
3
LotjaGi4g1v0188100.1
– Ferredoxin family protein; TAIR: AT1G32550.1 2Fe-2S ferredoxin-like superfamily protein; Swiss-Prot: sp|P08451|FER2_SYNP6 Ferredoxin-2; TrEMBL-Plants: tr|G7JGG5|G7JGG5_MEDTR 2Fe-2S ferredoxin superfamily protein; Found in the gene: LotjaGi4g1v0188100
GO terms
3
LotjaGi4g1v0307100.1
– Choline monooxygenase; TAIR: AT4G29890.1 choline monooxygenase, putative (CMO-like); Swiss-Prot: sp|Q9SZR0|CHMO_ARATH Choline monooxygenase, chloroplastic; TrEMBL-Plants: tr|I1MSJ9|I1MSJ9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0307100
GO terms
5
LotjaGi4g1v0320900.1
– 2Fe-2S ferredoxin; TAIR: AT4G21090.1 MITOCHONDRIAL FERREDOXIN 2; Swiss-Prot: sp|Q8S904|MFDX2_ARATH Adrenodoxin-like protein 2, mitochondrial; TrEMBL-Plants: tr|A0A067KCK0|A0A067KCK0_JATCU Uncharacterized protein; Found in the gene: LotjaGi4g1v0320900
GO terms
2
LotjaGi4g1v0375900.1
– Pheophorbide a oxygenase, chloroplastic; TAIR: AT4G25650.1 ACD1-like protein; Swiss-Prot: sp|Q8W496|PTC52_ARATH Protochlorophyllide-dependent translocon component 52, chloroplastic; TrEMBL-Plants: tr|G7LIM7|G7LIM7_MEDTR Chlorophyllide A oxygenase; Found in the gene: LotjaGi4g1v0375900
GO terms
3
LotjaGi4g1v0387900.1
– Ferredoxin; TAIR: AT1G60950.1 2Fe-2S ferredoxin-like superfamily protein; Swiss-Prot: sp|Q43517|FER1_SOLLC Ferredoxin-1, chloroplastic; TrEMBL-Plants: tr|I3S4Y2|I3S4Y2_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0387900
GO terms
3
LotjaGi4g1v0451800.1
– 2Fe-2S ferredoxin; TAIR: AT4G21090.1 MITOCHONDRIAL FERREDOXIN 2; Swiss-Prot: sp|Q8S904|MFDX2_ARATH Adrenodoxin-like protein 2, mitochondrial; TrEMBL-Plants: tr|I3SN88|I3SN88_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0451800
GO terms
2

Co-occuring GO terms 1

A list of co-occurring GO terms within the L. japonicus gene space:

GO term Namespace Name Observations Saturation (%)
GO:0051537
Molecular function 2 iron, 2 sulfur cluster binding 1 1.79