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IPR001937

Source: InterPro

Description

IPR001937 is a Galactose-1-phosphate uridyl transferase, class I.

<p>Galactose-1-phosphate uridyl transferase [ec:2.7.7.12] (GalT) catalyses the transfer of an uridyldiphosphate group on galactose (or glucose) 1-phosphate. During the reaction, the uridyl moiety links to a histidine residue. In the Escherichia coli enzyme, it has been shown [[cite:PUB00004352]] that two histidine residues separated by a single proline residue are essential for enzyme activity.</p> <p>On the basis of sequence similarities, two apparently unrelated families seem to exist. Class-I enzymes are found in eukaryotes as well as some bacteria such as E. coli or Streptomyces lividans, while class-II enzymes have been found so far only in bacteria such as Bacillus subtilis or Lactobacillus helveticus [[cite:PUB00002146]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0008108
Molecular function UDP-glucose:hexose-1-phosphate uridylyltransferase activity Catalysis of the reaction: alpha-D-galactose 1-phosphate + UDP-D-glucose = alpha-D-glucose 1-phosphate + UDP-D-galactose.
Subterm of
GO:0008270
Molecular function Zinc ion binding Interacting selectively and non-covalently with zinc (Zn) ions.
Subterm of
GO:0033499
Biological process Galactose catabolic process via UDP-galactose The chemical reactions and pathways resulting in the breakdown of galactose, via the intermediate UDP-galactose.
Subterm of

Associated Lotus transcripts 3

Transcript Name Description Predicted domains Domain count
Lj6g3v0227380.1
– PREDICTED: probable galactose-1-phosphate uridyl transferase-like [Glycine max] gi|356559549|ref|XP_003548061.1|
Domains
6
Lj6g3v0227390.1
– PREDICTED: probable galactose-1-phosphate uridyl transferase-like [Glycine max] gi|356559549|ref|XP_003548061.1|
Domains
10
LotjaGi6g1v0032000.1
– Galactose-1-phosphate uridylyltransferase; TAIR: AT5G18200.1 putative galactose-1-phosphate uridyltransferase; Swiss-Prot: sp|Q9FK51|AGLUP_ARATH ADP-glucose phosphorylase; TrEMBL-Plants: tr|I1MNU2|I1MNU2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0032000
Domains
10

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
TIGR00209 TIGRFAM 1 33.33