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IPR003131 is a Potassium channel tetramerisation-type BTB domain.
<p>This domain can be found at the N terminus of voltage-gated potassium channel proteins, where represents a cytoplasmic tetramerisation domain (T1) involved in assembly of alpha-subunits into functional tetrameric channels [[cite:PUB00006428]]. This domain can also be found in proteins that are not potassium channels, like KCTD1 (potassium channel tetramerisation domain-containing protein 1). KCTD1 is though to be a nuclear protein that functions as a transcriptional repressor. In KCTD1, the T1-type BTB domain mediates homomeric protein-protein interactions [[cite:PUB00058068], [cite:PUB00058069]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Biological process | Protein homooligomerization | The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: BTB/POZ domain-containing protein At2g24240-like [Cicer arietinum] gi|502149972|ref|XP_004507731.1| | 11 | ||
| – | BTB/POZ domain-containing protein; TAIR: AT3G09030.1 BTB/POZ domain-containing protein; Swiss-Prot: sp|Q9S7R7|Y3903_ARATH BTB/POZ domain-containing protein At3g09030; TrEMBL-Plants: tr|Q2HUH9|Q2HUH9_MEDTR BTB/POZ domain plant protein; Found in the gene: LotjaGi3g1v0225300 | 11 | ||
| – | BTB/POZ domain-containing protein; TAIR: AT2G24240.1 BTB/POZ domain with WD40/YVTN repeat-like protein; Swiss-Prot: sp|Q9ZUH1|Y2424_ARATH BTB/POZ domain-containing protein At2g24240; TrEMBL-Plants: tr|G7JGR0|G7JGR0_MEDTR Potassium channel tetramerization domain protein; Found in the gene: LotjaGi4g1v0287400 | 13 | ||
| – | BTB/POZ domain-containing protein; TAIR: AT5G41330.1 BTB/POZ domain with WD40/YVTN repeat-like protein; Swiss-Prot: sp|Q9FN67|Y5133_ARATH BTB/POZ domain-containing protein At5g41330; TrEMBL-Plants: tr|A0A072TV73|A0A072TV73_MEDTR BTB/POZ domain plant protein; Found in the gene: LotjaGi4g1v0427900 | 12 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd18316 | CDD | 1 | 25.00 |