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IPR003750

Source: InterPro

Description

IPR003750 is a Putative RNA methyltransferase C9orf114-like.

<p>This entry includes the putative methyltransferase C9orf114 from human, also known as SPOUT1, and its homologues [[cite:PUB00044735], [cite:PUB00057459]]. It is required for association of the centrosomes with the poles of the bipolar mitotic spindle during metaphase [[cite:PUB00158921], [cite:PUB00143243]]. It is also involved in chromosome alignment [[cite:PUB00158921]]. SPOUT1 binds specifically to miRNA MIR145 hairpin and regulates MIR145 expression at a postranscriptional level [[cite:PUB00089985]].</p> <p>Members of this family have a TIM barrel-like fold with a deep C-terminal trefoil knot. The arrangement of its hydrophilic and hydrophobic surfaces are opposite to that of the classic TIM barrel proteins.</p>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Associated Lotus transcripts 3

Transcript Name Description Predicted domains Domain count
Lj5g3v2058560.1
– OB-fold-like isoform 1 [Theobroma cacao] gi|508713706|gb|EOY05603.1|
Domains
9
LotjaGi5g1v0316800.1
– OB-fold-like, putative isoform 2; TAIR: AT5G19300.1 methyltransferase C9orf114 protein; Swiss-Prot: sp|Q5T280|CI114_HUMAN Putative methyltransferase C9orf114; TrEMBL-Plants: tr|I1NGB5|I1NGB5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0316800
Domains
12
LotjaGi5g1v0316800.2
– OB-fold-like, putative isoform 2; TAIR: AT5G19300.1 methyltransferase C9orf114 protein; Swiss-Prot: sp|Q5T280|CI114_HUMAN Putative methyltransferase C9orf114; TrEMBL-Plants: tr|I1NGB5|I1NGB5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0316800
Domains
12

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 33.33