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IPR004506 is a tRNA-specific 2-thiouridylase.
<p>This family represents tRNA-specific 2-thiouridylase (sometimes called tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase), which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine (mnm5s2U) present in the wobble position of some tRNAs [[cite:PUB00017420]]. This family of enzyme only presents in bacteria and eukaryote. The archaeal counterpart of this enzyme performs same function, but is completely unrelated in sequence [[cite:PUB00016823]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Biological process | TRNA processing | The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group. | ||
| Molecular function | Transferase activity | Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: tRNA-specific 2-thiouridylase MnmA-like [Cicer arietinum] gi|502148249|ref|XP_004507093.1| | 11 | ||
| – | PREDICTED: tRNA-specific 2-thiouridylase MnmA-like [Cicer arietinum] gi|502148249|ref|XP_004507093.1| | 5 | ||
| – | TRNA-specific 2-thiouridylase mnmA; TAIR: AT1G51310.1 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Swiss-Prot: sp|O51625|MNMA_BORBU tRNA-specific 2-thiouridylase MnmA; TrEMBL-Plants: tr|I1LJW0|I1LJW0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0492700 | 13 | ||
| – | TRNA-specific 2-thiouridylase mnmA; TAIR: AT1G51310.1 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Swiss-Prot: sp|O51625|MNMA_BORBU tRNA-specific 2-thiouridylase MnmA; TrEMBL-Plants: tr|K7LPK5|K7LPK5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0492700 | 12 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd01998 | CDD | 1 | 25.00 |