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IPR004556 is a Methyltransferase HemK-like.
<p>This entry includes HemK (also known as PrmC) from Escherichia coli. HemK methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif [[cite:PUB00043100], [cite:PUB00039505]]. Its homologue in Saccharomyces cerevisiae, Mtq1, is a methyltransferase that methylates MRF1 on 'Gln-287' using S-adenosyl L-methionine as methyl donor [[cite:PUB00063062]]. Homologues are found, usually in a single copy, in nearly all completed genomes, but varying somewhat in apparent domain architecture. Both Escherichia coli and Haemophilus influenzae have two members rather than one. The members from the Mycoplasmas have an additional C-terminal domain.</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Biological process | Protein methylation | The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom. | ||
| Molecular function | Protein methyltransferase activity | Catalysis of the transfer of a methyl group (CH3-) to a protein. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: protein methyltransferase hemK homolog [Glycine max] gi|356525752|ref|XP_003531487.1| | 12 | ||
| – | PREDICTED: protein methyltransferase hemK homolog [Glycine max] gi|356525752|ref|XP_003531487.1| | 12 | ||
| – | Methyltransferase; TAIR: AT5G64150.1 RNA methyltransferase family protein; Swiss-Prot: sp|Q8DHV7|PRMC_THEEB Release factor glutamine methyltransferase; TrEMBL-Plants: tr|A0A0B2SVL3|A0A0B2SVL3_GLYSO Release factor glutamine methyltransferase; Found in the gene: LotjaGi3g1v0135500 | 12 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd02440 | CDD | 1 | 33.33 |