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IPR004823 is a TATA box binding protein associated factor (TAF), histone-like fold domain.
<p>The TATA box binding protein associated factor (TAF) is part of the transcription initiation factor TFIID multimeric protein complex. TFIID plays a central role in mediating promoter responses to various activators and repressors. It binds tightly to TAFII-250 and directly interacts with TAFII-40. TFIID is composed of TATA binding protein (TBP) and a number of TBP-associated factors (TAFS). TAF proteins adopt a histone-like fold [[cite:PUB00075536], [cite:PUB00099783]].</p> <p>The DNA-binding general transcription factor complex TFIID is central to the initiation of DNA-dependent RNA polymerase II transcription. TFIID is the only general transcription initiation factor that bind to the TATA box. The binding of TFIID to the TATA-box is the first step in the formation of a complex able to initiate transcription [[cite:PUB00087636]]. TFIID consists of the TATA binding protein (TBP) and 14 TBP-associated factors (TAFs). One copy of each TAF1, TAF2, TAF3, TAF7, TAF8, TAF11, TAF13, two copies of each TAF4, TAF5, TAF6, TAF9, TAF10, TAF12, and three copies of TAF14 [[cite:PUB00087622]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Biological process | DNA-templated transcription, initiation | Any process involved in the assembly of the RNA polymerase preinitiation complex (PIC) at the core promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. The initiation phase ends just before and does not include promoter clearance, or release, which is the transition between the initiation and elongation phases of transcription. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: transcription initiation factor TFIID subunit 6-like [Glycine max] gi|356499648|ref|XP_003518649.1| | 9 | ||
| – | PREDICTED: transcription initiation factor TFIID subunit 6-like [Cicer arietinum] gi|502102626|ref|XP_004492136.1| | 9 | ||
| – | PREDICTED: transcription initiation factor TFIID subunit 6-like isoform 1 [Glycine max] gi|356527101|ref|XP_003532152.1| | 15 | ||
| – | Transcription initiation factor TFIID subunit 6; TAIR: AT1G04950.1 TATA BOX ASSOCIATED FACTOR II 59; Swiss-Prot: sp|Q9MAU3|TAF6_ARATH Transcription initiation factor TFIID subunit 6; TrEMBL-Plants: tr|A0A0L9UX09|A0A0L9UX09_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0539400 | 16 | ||
| – | Histone H4; TAIR: AT1G07660.1 Histone superfamily protein; Swiss-Prot: sp|P62785|H41_WHEAT Histone H4 variant TH011; TrEMBL-Plants: tr|K7VQC2|K7VQC2_MAIZE Histone H4; Found in the gene: LotjaGi2g1v0081300 | 16 | ||
| – | Histone H4; TAIR: AT1G07660.1 Histone superfamily protein; Swiss-Prot: sp|P84048|H4_ACRAS Histone H4; TrEMBL-Plants: tr|K7VQC2|K7VQC2_MAIZE Histone H4; Found in the gene: LotjaGi6g1v0129300 | 16 | ||
| – | Histone H4; TAIR: AT1G07660.1 Histone superfamily protein; Swiss-Prot: sp|P84048|H4_ACRAS Histone H4; TrEMBL-Plants: tr|K7VQC2|K7VQC2_MAIZE Histone H4; Found in the gene: LotjaGi6g1v0129500 | 16 | ||
| – | Histone H4; TAIR: AT1G07660.1 Histone superfamily protein; Swiss-Prot: sp|P84048|H4_ACRAS Histone H4; TrEMBL-Plants: tr|K7VQC2|K7VQC2_MAIZE Histone H4; Found in the gene: LotjaGi6g1v0129600 | 16 | ||
| – | Transcription initiation factor TFIID subunit 6; TAIR: AT1G04950.1 TATA BOX ASSOCIATED FACTOR II 59; Swiss-Prot: sp|Q9MAU3|TAF6_ARATH Transcription initiation factor TFIID subunit 6; TrEMBL-Plants: tr|A0A151SBK3|A0A151SBK3_CAJCA Transcription initiation factor TFIID subunit 6; Found in the gene: LotjaGi6g1v0153200 | 15 | ||
| – | Transcription initiation factor TFIID subunit 6; TAIR: AT1G04950.1 TATA BOX ASSOCIATED FACTOR II 59; Swiss-Prot: sp|Q9MAU3|TAF6_ARATH Transcription initiation factor TFIID subunit 6; TrEMBL-Plants: tr|A0A151SBK3|A0A151SBK3_CAJCA Transcription initiation factor TFIID subunit 6; Found in the gene: LotjaGi6g1v0153200 | 15 | ||
| – | Transcription initiation factor TFIID subunit 6; TAIR: AT1G04950.1 TATA BOX ASSOCIATED FACTOR II 59; Swiss-Prot: sp|Q9MAU3|TAF6_ARATH Transcription initiation factor TFIID subunit 6; TrEMBL-Plants: tr|A0A151SBK3|A0A151SBK3_CAJCA Transcription initiation factor TFIID subunit 6; Found in the gene: LotjaGi6g1v0153200 | 15 | ||
| – | Transcription initiation factor TFIID subunit 6; TAIR: AT1G04950.1 TATA BOX ASSOCIATED FACTOR II 59; Swiss-Prot: sp|Q9MAU3|TAF6_ARATH Transcription initiation factor TFIID subunit 6; TrEMBL-Plants: tr|A0A151SBK3|A0A151SBK3_CAJCA Transcription initiation factor TFIID subunit 6; Found in the gene: LotjaGi6g1v0153200 | 16 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 8.33 |