Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message
IPR005792 is a Protein disulphide isomerase.
<p>This family represents eukaryotic protein disulphide isomerases retained in the endoplasmic reticulum (ER) and other closely related forms [[cite:PUB00089633]]. Some members have been assigned alternative or additional functions such as prolyl 4-hydroxylase [[cite:PUB00089643], [cite:PUB00089642]]. Members of this family have at least two protein-disulphide domains, each similar to thioredoxin but with the redox-active disulphide in the motif PWCGHCK, and an ER retention signal at the extreme C terminus (KDEL, HDEL, and similar motifs).</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
GO term | Namespace | Name | Definition | Relationships |
---|---|---|---|---|
Molecular function | Protein disulfide isomerase activity | Catalysis of the rearrangement of both intrachain and interchain disulfide bonds in proteins. |
Transcript | Name | Description | Predicted domains | Domain count |
---|---|---|---|---|
– | Protein disulfide isomerase-like protein precursor [Glycine max] gi|351722359|ref|NP_001238009.1| | 31 | ||
– | Protein disulfide isomerase L-2 [Medicago truncatula] gi|357472209|ref|XP_003606389.1| | 30 | ||
– | Protein disulfide-isomerase; TAIR: AT1G77510.1 PDI-like 1-2; Swiss-Prot: sp|P29828|PDI_MEDSA Protein disulfide-isomerase; TrEMBL-Plants: tr|I7FST9|I7FST9_SOYBN Protein disulfide-isomerase; Found in the gene: LotjaGi1g1v0262100 | 30 | ||
– | Protein disulfide-isomerase; TAIR: AT5G60640.1 PDI-like 1-4; Swiss-Prot: sp|Q9FF55|PDI14_ARATH Protein disulfide isomerase-like 1-4; TrEMBL-Plants: tr|G7JPD1|G7JPD1_MEDTR Protein disulfide-isomerase; Found in the gene: LotjaGi2g1v0360200 | 29 | ||
– | Protein disulfide-isomerase; TAIR: AT5G60640.1 PDI-like 1-4; Swiss-Prot: sp|Q9FF55|PDI14_ARATH Protein disulfide isomerase-like 1-4; TrEMBL-Plants: tr|A0A0R0HDA3|A0A0R0HDA3_SOYBN Protein disulfide-isomerase; Found in the gene: LotjaGi3g1v0162500 | 28 |
A list of co-occurring predicted domains within the L. japonicus gene space:
Predicted domain | Source | Observations | Saturation (%) |
---|---|---|---|
mobidb-lite | MobiDBLite | 1 | 20.00 |